{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:47:55Z","timestamp":1764784075119},"reference-count":56,"publisher":"Impact Journals, LLC","issue":"32","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2018,4,27]]},"DOI":"10.18632\/oncotarget.25237","type":"journal-article","created":{"date-parts":[[2018,4,27]],"date-time":"2018-04-27T21:44:08Z","timestamp":1524865448000},"page":"22785-22801","source":"Crossref","is-referenced-by-count":8,"title":["Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma"],"prefix":"10.18632","volume":"9","author":[{"given":"Stefania","family":"Augeri","sequence":"first","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Capano","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Morone","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Fissolo","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Giacomino","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Peola","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahida","family":"Drace","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida","family":"Rapa","sequence":"additional","affiliation":[{"name":"Department of Oncology, University of Torino, San Luigi Hospital, Torino 10043, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Novello","sequence":"additional","affiliation":[{"name":"Department of Oncology, University of Torino, San Luigi Hospital, Torino 10043, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Volante","sequence":"additional","affiliation":[{"name":"Department of Oncology, University of Torino, San Luigi Hospital, Torino 10043, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisella","family":"Righi","sequence":"additional","affiliation":[{"name":"Department of Oncology, University of Torino, San Luigi Hospital, Torino 10043, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enza","family":"Ferrero","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Ortolan","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ada","family":"Funaro","sequence":"additional","affiliation":[{"name":"Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino 10126, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2018,4,27]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1183\/09059180.00007014","article-title":"Malignant pleural mesothelioma: history, controversy and future of a manmade epidemic","volume":"24","author":"Stella","year":"2015","journal-title":"Eur Respir Rev"},{"key":"2","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1183\/16000617.0063-2016","article-title":"Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment","volume":"25","author":"Psallidas","year":"2016","journal-title":"Eur Respir Rev"},{"key":"3","doi-asserted-by":"publisher","first-page":"6881","DOI":"10.1200\/JCO.20005.14.589","article-title":"Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada","volume":"23","author":"Giaccone","year":"2005","journal-title":"J Clin Oncol"},{"key":"4","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1093\/bmb\/ldp047","article-title":"Malignant mesothelioma","volume":"93","author":"Rudd","year":"2010","journal-title":"Br Med Bull"},{"key":"5","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1097\/PAT.0b013e32835bc848","article-title":"A diagnosis of malignant pleural mesothelioma can be made by effusion cytology: results of a 20 year audit","volume":"45","author":"Creaney","year":"2013","journal-title":"Pathology"},{"key":"6","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s12032-013-0649-x","article-title":"Clinical value of mesothelin in pleural effusions versus histology by medical thoracoscopy: brief report","volume":"30","author":"Roncella","year":"2013","journal-title":"Med Oncol"},{"key":"7","doi-asserted-by":"publisher","first-page":"53751","DOI":"10.18632\/oncotarget.17910","article-title":"Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?","volume":"8","author":"Vermaelen","year":"2017","journal-title":"Oncotarget"},{"key":"8","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s002510050654","article-title":"The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene","volume":"49","author":"Malavasi","year":"1999","journal-title":"Immunogenetics"},{"key":"9","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1152\/physrev.00035.2007","article-title":"Evolution and function of the ADP ribosyl cyclase\/CD38 gene family in physiology and pathology","volume":"88","author":"Aydin","year":"2008","journal-title":"Physiol Rev"},{"key":"10","doi-asserted-by":"crossref","first-page":"986","DOI":"10.2741\/4262","article-title":"The ADP-ribosyl cyclases\u2014the current evolutionary state of the ARCs","volume":"19","author":"Malavasi","year":"2014","journal-title":"Front Biosci (Landmark Ed)"},{"key":"11","doi-asserted-by":"publisher","first-page":"15923","DOI":"10.1038\/s41598-017-16184-w","article-title":"Human canonical CD157\/Bst1 is an alternatively spliced isoform masking a previously unidentified primate-specific exon included in a novel transcript","volume":"7","author":"Fiorio Pla","year":"2017","journal-title":"Sci Rep"},{"key":"12","first-page":"929","article-title":"Ectoenzymes and innate immunity: the role of human CD157 in leukocyte trafficking","volume":"14","author":"Malavasi","year":"2009","journal-title":"Front Biosci (Landmark Ed)"},{"key":"13","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/art.1780390414","article-title":"Elevated levels of the soluble form of bone marrow stromal cell antigen 1 in the sera of patients with severe rheumatoid arthritis","volume":"39","author":"Hirano","year":"1996","journal-title":"Arthritis Rheum"},{"key":"14","doi-asserted-by":"publisher","first-page":"4269","DOI":"10.1182\/blood-2004-06-2129","article-title":"CD157 is an important mediator of neutrophil adhesion and migration","volume":"104","author":"Malavasi","year":"2004","journal-title":"Blood"},{"key":"15","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/cbf.978","article-title":"CD157, the Janus of CD38 but with a unique personality","volume":"20","author":"Malavasi","year":"2002","journal-title":"Cell Biochem Funct"},{"key":"16","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1182\/blood-2006-04-017160","article-title":"CD157 plays a pivotal role in neutrophil transendothelial migration","volume":"108","author":"Funaro","year":"2006","journal-title":"Blood"},{"key":"17","doi-asserted-by":"crossref","first-page":"5325","DOI":"10.1073\/pnas.91.12.5325","article-title":"BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth","volume":"91","author":"Hirano","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"18","doi-asserted-by":"publisher","first-page":"35707","DOI":"10.18632\/oncotarget.16060","article-title":"Targeting CD157 in AML using a novel, Fc-engineered antibody construct","volume":"8","author":"Aud","year":"2017","journal-title":"Oncotarget"},{"key":"19","doi-asserted-by":"publisher","first-page":"15588","DOI":"10.1074\/jbc.M113.535070","article-title":"Binding of CD157 protein to fibronectin regulates cell adhesion and spreading","volume":"289","author":"Funaro","year":"2014","journal-title":"J Biol Chem"},{"key":"20","doi-asserted-by":"crossref","first-page":"366","DOI":"10.2741\/4213","article-title":"CD157 at the intersection between leukocyte trafficking and epithelial ovarian cancer invasion","volume":"19","author":"Funaro","year":"2014","journal-title":"Front Biosci (Landmark Ed)"},{"key":"21","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1002\/cyto.b.21092","article-title":"CD38 and CD157: A long journey from activation markers to multifunctional molecules","volume":"84","author":"Malavasi","year":"2013","journal-title":"Cytometry B Clin Cytom"},{"key":"22","doi-asserted-by":"publisher","first-page":"e43649","DOI":"10.1371\/journal.pone.0043649","article-title":"Overexpression of CD157 contributes to epithelial ovarian cancer progression by promoting mesenchymal differentiation","volume":"7","author":"Funaro","year":"2012","journal-title":"PLoS One"},{"key":"23","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1093\/jnci\/djq256","article-title":"Functional Role and prognostic significance of CD157 in ovarian carcinoma","volume":"105","author":"Funaro","year":"2010","journal-title":"J Natl Cancer Inst"},{"key":"24","doi-asserted-by":"publisher","first-page":"6191","DOI":"10.18632\/oncotarget.2186","article-title":"CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome","volume":"5","author":"Funaro","year":"2014","journal-title":"Oncotarget"},{"key":"25","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1042\/bj3570385","article-title":"Site-directed removal of N-glycosylation sites in BST-1\/CD157: effects on molecular and functional heterogeneity","volume":"357","author":"Jingami","year":"2001","journal-title":"Biochem J"},{"key":"26","doi-asserted-by":"publisher","first-page":"18681","DOI":"10.1074\/jbc.M111.227876","article-title":"The CD157-integrin partnership controls transendothelial migration and adhesion of human monocytes","volume":"286","author":"Funaro","year":"2011","journal-title":"J Biol Chem"},{"key":"27","doi-asserted-by":"publisher","first-page":"E968","DOI":"10.1073\/pnas.1521230113","article-title":"Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes","volume":"113","author":"Thery","year":"2016","journal-title":"Proc Natl Acad Sci U S A"},{"key":"28","doi-asserted-by":"publisher","first-page":"4336","DOI":"10.1182\/blood-2003-03-0871","article-title":"Lipid raft-associated protein sorting in exosomes","volume":"102","author":"Vidal","year":"2003","journal-title":"Blood"},{"key":"29","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1146\/annurev-cellbio-101512-122326","article-title":"Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles","volume":"30","author":"Thery","year":"2014","journal-title":"Annu Rev Cell Dev Biol"},{"key":"30","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1172\/JCI81129","article-title":"Extracellular vesicle isolation and characterization: toward clinical application","volume":"126","author":"Simpson","year":"2016","journal-title":"J Clin Invest"},{"key":"31","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.ymeth.2015.03.009","article-title":"An optimized procedure for exosome isolation and analysis using serum samples: Application to cancer biomarker discovery","volume":"87","author":"Vlassov","year":"2015","journal-title":"Methods"},{"key":"32","doi-asserted-by":"publisher","first-page":"32643","DOI":"10.1038\/srep32643","article-title":"Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo","volume":"6","author":"Simpson","year":"2016","journal-title":"Sci Rep"},{"key":"33","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1016\/S0002-9440(10)63739-X","article-title":"Proteomic analysis of exosomes secreted by human mesothelioma cells","volume":"164","author":"Lambrecht","year":"2004","journal-title":"Am J Pathol"},{"key":"34","doi-asserted-by":"publisher","first-page":"647","DOI":"10.5858\/arpa.2012-0214-OA","article-title":"Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group","volume":"137","author":"Fraire","year":"2013","journal-title":"Arch Pathol Lab Med"},{"key":"35","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1136\/jclinpath-2013-201609","article-title":"Challenges and controversies in the diagnosis of malignant mesothelioma: Part 2. Malignant mesothelioma subtypes, pleural synovial sarcoma, molecular and prognostic aspects of mesothelioma, BAP1, aquaporin-1 and microRNA","volume":"66","author":"Klebe","year":"2013","journal-title":"J Clin Pathol"},{"key":"36","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1002\/dc.21303","article-title":"The sensitivity of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma","volume":"38","author":"Soomro","year":"2010","journal-title":"Diagn Cytopathol"},{"key":"37","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1053\/j.semtcvs.2009.06.007","article-title":"Current status of screening for malignant pleural mesothelioma","volume":"21","author":"Carbone","year":"2009","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"38","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1038\/bjc.2017.22","article-title":"Prognostication and monitoring of mesothelioma using biomarkers: a systematic review","volume":"116","author":"Maskell","year":"2017","journal-title":"Br J Cancer"},{"key":"39","doi-asserted-by":"publisher","first-page":"259","DOI":"10.21037\/tlcr.2017.05.06","article-title":"Diagnostic and prognostic biomarkers for malignant mesothelioma: an update","volume":"6","author":"Yang","year":"2017","journal-title":"Transl Lung Cancer Res"},{"key":"40","doi-asserted-by":"publisher","first-page":"2918","DOI":"10.1158\/0008-5472.CAN-05-4003","article-title":"Global gene expression profiling of circulating endothelial cells in patients with metastatic carcinomas","volume":"66","author":"O\u2019Hara","year":"2006","journal-title":"Cancer Res"},{"key":"41","doi-asserted-by":"publisher","first-page":"1612","DOI":"10.1016\/S0140-6736(03)14794-0","article-title":"Mesothelin-family proteins and diagnosis of mesothelioma","volume":"362","author":"Hellstrom","year":"2003","journal-title":"Lancet"},{"key":"42","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1136\/thx.2006.068114","article-title":"Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma","volume":"62","author":"Robinson","year":"2007","journal-title":"Thorax"},{"key":"43","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1517\/17530059.1.1.137","article-title":"MESOMARK((R)) in vitro diagnostic test for mesothelioma","volume":"1","author":"Allard","year":"2007","journal-title":"Expert Opin Med Diagn"},{"key":"44","doi-asserted-by":"publisher","first-page":"2928","DOI":"10.1158\/1078-0432.CCR-06-2144","article-title":"Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment","volume":"13","author":"Lassalle","year":"2007","journal-title":"Clin Cancer Res"},{"key":"45","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.1097\/JTO.0b013e3182272294","article-title":"Soluble mesothelin, megakaryocyte potentiating factor, and osteopontin as markers of patient response and outcome in mesothelioma","volume":"6","author":"van Meerbeeck","year":"2011","journal-title":"J Thorac Oncol"},{"key":"46","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1056\/NEJMoa1115050","article-title":"Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma","volume":"367","author":"Liu","year":"2012","journal-title":"N Engl J Med"},{"key":"47","doi-asserted-by":"publisher","first-page":"244","DOI":"10.21037\/atm.2017.06.60","article-title":"Diagnosis and prognosis-review of biomarkers for mesothelioma","volume":"5","author":"Pass","year":"2017","journal-title":"Ann Transl Med"},{"key":"48","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.chest.2016.12.004","article-title":"Malignant Mesothelioma Biomarkers: From Discovery to Use in Clinical Practice for Diagnosis, Monitoring, Screening, and Treatment","volume":"152","author":"Robinson","year":"2017","journal-title":"Chest"},{"key":"49","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/nrc.2017.42","article-title":"Novel insights into mesothelioma biology and implications for therapy","volume":"17","author":"Fennell","year":"2017","journal-title":"Nat Rev Cancer"},{"key":"50","doi-asserted-by":"publisher","first-page":"S99","DOI":"10.1016\/j.lungcan.2005.03.018","article-title":"Transcriptional profiling of mesothelioma using microarrays","volume":"49","author":"Gordon","year":"2005","journal-title":"Lung Cancer"},{"key":"51","doi-asserted-by":"publisher","first-page":"e1278330","DOI":"10.1080\/2162402X.2016.1278330","article-title":"Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma","volume":"6","author":"Vigneswaran","year":"2017","journal-title":"Oncoimmunology"},{"key":"52","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1158\/0008-5472.CAN-14-1008","article-title":"Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma","volume":"75","author":"Pass","year":"2015","journal-title":"Cancer Res"},{"key":"53","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/s12885-015-1301-2","article-title":"Epidemiological patterns of asbestos exposure and spatial clusters of incident cases of malignant mesothelioma from the Italian national registry","volume":"15","author":"Chellini","year":"2015","journal-title":"BMC Cancer"},{"key":"54","doi-asserted-by":"publisher","first-page":"S37","DOI":"10.1016\/j.lungcan.2004.04.027","article-title":"Aberrant E-cadherin and gamma-catenin expression in malignant mesothelioma and its diagnostic and biological relevance","volume":"45","author":"Betta","year":"2004","journal-title":"Lung Cancer"},{"key":"55","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1002\/0471143030.cb0322s30","article-title":"Isolation and characterization of exosomes from cell culture supernatants and biological fluids","author":"Clayton","year":"2006","journal-title":"Curr Protoc Cell Biol"},{"key":"56","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1158\/1078-0432.CCR-04-1688","article-title":"Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells","volume":"11","author":"Altevogt","year":"2005","journal-title":"Clin Cancer Res"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.25237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T16:47:47Z","timestamp":1589042867000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.25237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,27]]},"references-count":56,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2018,4,27]]}},"alternative-id":["25237","29854315"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.25237","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,27]]}}}