{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T02:48:31Z","timestamp":1726368511507},"reference-count":27,"publisher":"Impact Journals, LLC","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2016,3,22]]},"DOI":"10.18632\/oncotarget.7699","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T12:52:03Z","timestamp":1456404723000},"page":"14963-14972","source":"Crossref","is-referenced-by-count":5,"title":["Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients"],"prefix":"10.18632","volume":"7","author":[{"given":"Hao","family":"Peng","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Long","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Fei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Ping","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Zhi","family":"Liu","sequence":"additional","affiliation":[{"name":"Imaging Diagnosis and Interventional Center, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Tian","sequence":"additional","affiliation":[{"name":"Imaging Diagnosis and Interventional Center, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai-Hua","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2016,2,25]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3322\/caac.20107","article-title":"Global cancer statistics","volume":"61","author":"Forman","year":"2011","journal-title":"CA Cancer J Clin"},{"key":"2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.radonc.2010.04.006","article-title":"Factors associated with overall survival in 1706 patients with nasopharyngeal carcinoma: significance of intensive neoadjuvant chemotherapy and radiation break","volume":"96","author":"Kong","year":"2010","journal-title":"Radiother Oncol"},{"key":"3","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1056\/NEJMoa032260","article-title":"Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma","volume":"350","author":"Jiang","year":"2004","journal-title":"N Engl J Med"},{"key":"4","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1016\/j.ijrobp.2007.02.012","article-title":"Long-term prognostic effects of plasma epstein-barr virus DNA by minor groove binder-probe real-time quantitative PCR on nasopharyngeal carcinoma patients receiving concurrent chemoradiotherapy","volume":"68","author":"Shen","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"5","first-page":"5452","article-title":"Quantitative and temporal correlation between circulating cell-free Epstein-Barr virus DNA and tumor recurrence in nasopharyngeal carcinoma","volume":"59","author":"Huang","year":"1999","journal-title":"Cancer Res"},{"key":"6","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.radonc.2012.09.001","article-title":"Is primary tumor volume still a prognostic factor in intensity modulated radiation therapy for nasopharyngeal carcinoma?","volume":"104","author":"Ma","year":"2012","journal-title":"Radiother Oncol"},{"key":"7","first-page":"247","article-title":"Impact of primary tumor volume and location on the prognosis of patients with locally recurrent nasopharyngeal carcinoma","volume":"34","author":"Han","year":"2015","journal-title":"Chin J Cancer"},{"key":"8","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1016\/j.ejca.2013.03.008","article-title":"High pretreatment serum lactate dehydrogenase level correlates with disease relapse and predicts an inferior outcome in locally advanced nasopharyngeal carcinoma","volume":"49","author":"Chen","year":"2013","journal-title":"Eur J Cancer"},{"key":"9","doi-asserted-by":"crossref","first-page":"12242","DOI":"10.1038\/srep12242","article-title":"Prognostic value of the primary lesion apparent diffusion coefficient (ADC) in nasopharyngeal carcinoma: a retrospective study of 541 cases","volume":"5","author":"Ma","year":"2015","journal-title":"Sci Rep"},{"key":"10","article-title":"Nasopharyngeal carcinoma","author":"Chan","year":"2015","journal-title":"Lancet"},{"key":"11","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1148\/radiol.15154020","article-title":"Prognostic Value of Cervical Nodal Necrosis in Nasopharyngeal Carcinoma: Analysis of 1800 Patients with Positive Cervical Nodal Metastasis at MR Imaging","volume":"276","author":"Lu","year":"2015","journal-title":"Radiology"},{"key":"12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.radonc.2013.05.017","article-title":"Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial","volume":"108","author":"West","year":"2013","journal-title":"Radiother Oncol"},{"key":"13","first-page":"337","article-title":"Radioresistance parameters in head and neck cancers and methods to radiosensitize. [Article in French]","volume":"19","author":"Lapeyre","year":"2015","journal-title":"Cancer Radiother"},{"key":"14","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0360-3016(97)00101-6","article-title":"Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck","volume":"38","author":"Dewhirst","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"15","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.radonc.2011.03.004","article-title":"Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck\u2014a systematic review and meta-analysis","volume":"100","author":"Overgaard","year":"2011","journal-title":"Radiother Oncol"},{"key":"16","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S1053-4296(96)80032-4","article-title":"Modification of Hypoxia-Induced Radioresistance in Tumors by the Use of Oxygen and Sensitizers","volume":"6","author":"Horsman","year":"1996","journal-title":"Semin Radiat Oncol"},{"key":"17","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/(SICI)1097-0215(19980821)79:4<365::AID-IJC10>3.0.CO;2-4","article-title":"Tumor hypoxia in pelvic recurrences of cervical cancer","volume":"79","author":"Vaupel","year":"1998","journal-title":"Int J Cancer"},{"key":"18","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1046\/j.1563-258X.2002.02032.x","article-title":"Hypoxia in breast cancer: pathogenesis, characterization and biological\/therapeutic implications","volume":"152","author":"Hockel","year":"2002","journal-title":"Wien Med Wochenschr"},{"key":"19","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1089\/ars.2007.1628","article-title":"Detection and characterization of tumor hypoxia using pO2 histography","volume":"9","author":"Mayer","year":"2007","journal-title":"Antioxid Redox Signal"},{"key":"20","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.tracli.2004.11.005","article-title":"Hypoxia and anemia: effects on tumor biology and treatment resistance","volume":"12","author":"Mayer","year":"2005","journal-title":"Transfus Clin Biol"},{"key":"21","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/0-387-26206-7_44","article-title":"Hypoxia in breast cancer: role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion","volume":"566","author":"Hockel","year":"2005","journal-title":"Adv Exp Med Biol"},{"key":"22","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0076-6879(04)81023-1","article-title":"Tumor hypoxia and malignant progression","volume":"381","author":"Hockel","year":"2004","journal-title":"Methods Enzymol"},{"key":"23","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1385\/MO:18:4:243","article-title":"Treatment resistance of solid tumors: role of hypoxia and anemia","volume":"18","author":"Hoeckel","year":"2001","journal-title":"Med Oncol"},{"key":"24","article-title":"Intensity-modulated proton therapy for nasopharyngeal carcinoma: Decreased radiation dose to normal structures and encouraging clinical outcomes","author":"Frank","year":"2015","journal-title":"Head Neck"},{"key":"25","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","article-title":"The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM","volume":"17","author":"Compton","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0009-9260(96)80265-0","article-title":"MRI features of cervical nodal necrosis in metastatic disease","volume":"51","author":"Khoo","year":"1996","journal-title":"Clin Radiol"},{"key":"27","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1148\/radiol.2303030157","article-title":"Necrosis in metastatic neck nodes: diagnostic accuracy of CT, MR imaging, and US","volume":"230","author":"Van Hasselt","year":"2004","journal-title":"Radiology"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.7699","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T18:55:00Z","timestamp":1589223300000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.7699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,25]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,3,22]]}},"alternative-id":["7699","26934649"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.7699","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,25]]}}}