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An 18-year-old man presented with right-sided nasal obstruction and epistaxis. Imaging revealed a large destructive mass in the right maxillary sinus that was suspicious for malignancy, including osteosarcoma. Endoscopic biopsy showed nonspecific benign osseous features that were discordant with the radiological findings. For this reason, endoscopic medial maxillectomy was performed. Histopathological examination with CD31 and CD34 immunostaining confirmed intraosseous venous hemangioma. Intraosseous hemangioma should be considered in the differential diagnosis of aggressive-appearing sinonasal masses, especially when imaging and biopsy findings are discordant, as its recognition may help prevent unnecessarily aggressive treatment.<\/jats:p>","DOI":"10.18787\/jr.2026.00012","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:16:08Z","timestamp":1785284168000},"page":"126-130","update-policy":"https:\/\/doi.org\/10.18787\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Huge Intraosseous Hemangioma in the Maxillary Sinus Misdiagnosed as Osteosarcoma: A Case Report"],"prefix":"10.18787","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1233-5815","authenticated-orcid":true,"given":"So Hee","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4529-0254","authenticated-orcid":true,"given":"Myeong Sang","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7989","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1592087","type":"journal-article"},{"key":"ref2","first-page":"1383","type":"journal-article","volume-title":"Intraosseous hemangioma of the zygoma: CT and MR findings","author":"Moore","year":"2001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/217349","type":"journal-article"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s0194-59980300465-0","type":"journal-article"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.omsc.2020.100147","type":"journal-article"}],"container-title":["Journal of Rhinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/j-rhinology.org\/upload\/pdf\/jr-2026-00012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/j-rhinology.org\/journal\/view.php?doi=10.18787\/jr.2026.00012","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/j-rhinology.org\/upload\/pdf\/jr-2026-00012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T05:53:51Z","timestamp":1785736431000},"score":1,"resource":{"primary":{"URL":"http:\/\/j-rhinology.org\/journal\/view.php?doi=10.18787\/jr.2026.00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,31]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,7]]}},"URL":"https:\/\/doi.org\/10.18787\/jr.2026.00012","relation":{},"ISSN":["1229-1498","2384-4361"],"issn-type":[{"value":"1229-1498","type":"print"},{"value":"2384-4361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,31]]},"assertion":[{"value":"2026-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}