{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T09:08:34Z","timestamp":1779095314329,"version":"3.51.4"},"reference-count":0,"publisher":"RCVS Knowledge","issue":"2","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["VE"],"abstract":"<jats:p>PICO Question\nIn dogs undergoing brachycephalic airway obstruction syndrome (BOAS) surgery does intraoperative constant rate infusion (CRI) of metoclopramide reduce the risk of regurgitation in the perioperative period?\n\u00a0\nClinical bottom line\nCategory of research\nTreatment.\nNumber and type of study designs reviewed\nThere were no publications that directly answered the PICO question. Two studies were identified which combined the use of metoclopramide in combination with other measures to reduce perioperative regurgitation.\nStrength of evidence\nZero.\nOutcomes reported\nThere is no data that solely assesses the effect of metoclopramide on gastro-oesophageal reflux in brachycephalic patients undergoing airway surgery.\nConclusion\nGiven the lack of evidence relating to the PICO question, the decision to use metoclopramide is based on personal preference and experience. Other medications and anaesthetic protocols that have been shown to reduce perioperative regurgitation should be considered first.<\/jats:p>","DOI":"10.18849\/ve.v11i2.738","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:30:47Z","timestamp":1779093047000},"source":"Crossref","is-referenced-by-count":0,"title":["Does a metoclopramide CRI reduce the risk of regurgitation associated with BOAS surgery in dogs?"],"prefix":"10.18849","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4245-3861","authenticated-orcid":false,"given":"Neil","family":"Fraser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8083","published-online":{"date-parts":[[2026,5,18]]},"container-title":["Veterinary Evidence"],"original-title":[],"link":[{"URL":"https:\/\/veterinaryevidence.org\/index.php\/ve\/article\/download\/738\/1196","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/veterinaryevidence.org\/index.php\/ve\/article\/download\/738\/1196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:30:48Z","timestamp":1779093048000},"score":1,"resource":{"primary":{"URL":"https:\/\/veterinaryevidence.org\/index.php\/ve\/article\/view\/738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,4,14]]}},"URL":"https:\/\/doi.org\/10.18849\/ve.v11i2.738","relation":{},"ISSN":["2396-9776"],"issn-type":[{"value":"2396-9776","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,18]]}}}