{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:43:28Z","timestamp":1792712608717,"version":"4.5.0"},"reference-count":0,"publisher":"Ethnicity and Disease Inc","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ethn Dis"],"abstract":"<p><strong>Introduction: <\/strong>Recruiting racial, ethnic, and other underserved minorities into conven\u00adtional clinic-based and other trials is known to be challenging. The Sistas Inspiring Sistas Through Activity and Support (SISTAS) Pro\u00adgram was a one-year randomized controlled trial (RCT) to promote physical activity and healthy eating among AA women in SC to reduce inflammatory biomarkers, which are linked to increased breast cancer (BrCa) risk and mortality. This study describes the development, recruitment, and imple\u00admentation of the SISTAS clinical trial and provides baseline characteristics of the study participants.<\/p><p><strong>Methods: <\/strong>SISTAS was developed using community-based participatory research (CBPR) approaches. At baseline, study participants completed assessments and underwent clinical measurements and blood draws to measure C-reactive protein (CRP) and interleukin-6 (IL-6). Participants randomized to the intervention received 12 weekly classes followed by nine monthly booster sessions. Post-intervention mea\u00adsurements were assessed at 12-week and 12-month follow-ups.<\/p><p><strong>Results: <\/strong>We recruited a total of 337 women who tended to: be middle-aged (mean age 48.2 years); have some college education; be employed full-time; have Medicare as their primary insurance; be non-smokers; and perceive their personal health as good. On average, the women were pre-hyper\u00adtensive at baseline (mean systolic blood pressure = 133.9 mm Hg; mean diastolic blood pressure = 84.0 mm Hg) and mor\u00adbidly obese (mean BMI &gt;40.0 kg\/m2); the mean fat mass and fat-free mass among participants were 106.4 lb and 121.0 lb, respectively.<\/p><p><strong>Conclusion: <\/strong>The SISTAS RCT addresses some of the gaps in the literature with respect to CBPR interventions target\u00ading AA women, such as implementing diet and physical activity in CBPR-based studies to decrease BrCa risk.<\/p><p><em>Ethn Dis. <\/em>2018;28(2):75-84; doi:10.18865\/ ed.28.2.75.<\/p><\/jats:p>","DOI":"10.18865\/ed.28.2.75","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T14:55:35Z","timestamp":1524754535000},"page":"75","source":"Crossref","is-referenced-by-count":7,"title":["Sistas Inspiring Sistas Through Activity and Support (SISTAS): Study Design and Demographics of Participants"],"prefix":"10.18865","volume":"28","author":[{"given":"Malcolm","family":"Bevel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oluwole A.","family":"Babatunde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue P.","family":"Heiney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather M.","family":"Brandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Wirth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Hurley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samira","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiluv","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra M.","family":"Wineglass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana Y.","family":"Warren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Angela","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Sercy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda S.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Hebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swann Arp","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18154","published-online":{"date-parts":[[2018,4,26]]},"container-title":["Ethnicity & Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/viewFile\/777\/1116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/viewFile\/777\/1127","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/download\/777\/1116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T17:42:51Z","timestamp":1552066971000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/view\/777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,26]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,4,26]]}},"URL":"https:\/\/doi.org\/10.18865\/ed.28.2.75","relation":{},"ISSN":["1945-0826","1049-510X"],"issn-type":[{"value":"1945-0826","type":"electronic"},{"value":"1049-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4,26]]}}}