{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T13:41:12Z","timestamp":1785159672087,"version":"3.55.0"},"reference-count":0,"publisher":"Ethnicity and Disease Inc","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ethn Dis"],"abstract":"<jats:p>Background: Stroke is a heterogeneous, catastrophic disease. A comprehensive clinical analysis of ischemic stroke (IS) risk factors and outcomes is crucial for optimum management in resource-poor settings.Methods: A prospective cross-sectional study of acute cerebrovascular disease (ACVD) involving 592 patients was con\u00adducted in a tertiary care center in Sri Lanka from November 2018 to May 2019. We aimed to describe the ACVD subtypes and the relationship of IS subtypes and subtype-categories (as defined by the Oxfordshire Community Stroke Project clinical clas\u00adsification) with risk factors, severity, and outcome.Results: The majority (63.3%) had IS. Partial anterior circulation syndromes (PACS), total anterior circulation syndrome (TACS), posterior circulation syndromes (POCS), and lacunar syndromes (LACS) accounted for 102 (29.7%), 58 (16.9%), 88 (25.7%) and 95 (27.7%) of the cases, respectively. The most common PACS sub-category was higher-cerebral-dysfunction-with-homonymous-hemianopia (HCD+HH,39 cases;38.2%). Cerebellar-signs-without-long-tract-signs (CS-LTS) sub-category constituted the highest among POCS (47 cases; 53.4%). The leading sub-category within LACS was pure-motor (PM) strokes (43 cases; 45.3%).Patients aged \u226550 years (adjusted-OR [AOR]2.439; 95%CI,1.163-5.116;P=.018), IHD(AOR 2.520; 95%CI,1.347-4.713; P=.004) and BMI&gt;23kg\/m2(AOR 2.607; 95% CI,1.420-4.784; P=.002) were 2.5 times more likely to associate with TACS. Patients with a history of TIA (AOR 1.910; 95%CI,1.036-3.524; P=.038) and arrhyth\u00admias (AOR 5.933; 95%CI,3.294-10.684; P&lt;.001) were 1.9 and 5.9 times more likely to be associated with POCS respectively. Those with hypertension were 2.3 times more likely to associate with LACS (AOR 2.233; 95%CI,1.270-3.926; P=.005).NIHSS(P&lt;.001), mRS on admission (P=.001) and in 3 months (P&lt;.001), deaths during hospital stay (P=.003) and within 28 days (P&lt;.001) had a stronger relationship with individual stroke subtypes.Conclusion: The comparative risk of different IS subtypes depends on differ\u00adent risk factors. The findings of this study demonstrate that sub-categories within each stroke subtype may behave independently with regard to risk factors and outcomes, thus warranting the need for individual assessment. Ethn Dis. 2021;31(4):509-518; doi:10.18865\/ed.31.4.509<\/jats:p>","DOI":"10.18865\/ed.31.4.509","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T14:40:38Z","timestamp":1634827238000},"page":"509-518","source":"Crossref","is-referenced-by-count":5,"title":["Ischemic Stroke Subtypes: Socio-demographic Factors, Risk Factors, and Outcomes in Southern Sri Lanka"],"prefix":"10.18865","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7106-1404","authenticated-orcid":false,"given":"Sathyajith Buddhika","family":"Ambawatte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8345-4950","authenticated-orcid":false,"given":"Dulmini Nadeesha","family":"Weerathunga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athula","family":"Dissanayake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surangi Chandhi","family":"Somaratne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanishka","family":"Athukorala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7260-1727","authenticated-orcid":false,"given":"Piyumi Sachindra Alwis","family":"Wijewickrama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18154","published-online":{"date-parts":[[2021,10,21]]},"container-title":["Ethnicity &amp; Disease"],"original-title":[],"link":[{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/viewFile\/1595\/2290","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/viewFile\/1595\/2301","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/download\/1595\/2290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T16:19:37Z","timestamp":1634833177000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ethndis.org\/edonline\/index.php\/ethndis\/article\/view\/1595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,21]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,10,21]]}},"URL":"https:\/\/doi.org\/10.18865\/ed.31.4.509","relation":{},"ISSN":["1945-0826","1049-510X"],"issn-type":[{"value":"1945-0826","type":"electronic"},{"value":"1049-510X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10,21]]}}}