{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T11:27:24Z","timestamp":1648639644790},"reference-count":54,"publisher":"Springer Publishing Company","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2000,2]]},"abstract":"<jats:p>Symptomatic calcium disorders\u2014most notably, hypocalcemia\u2014 are common problems in preterm and certain term infants. Many factors predispose susceptible neonates to hypo- or hypercalcemia, but in many cases, the root of the problem is altered function of the parathyroid glands. Parathyroid gland dysfunction may affect calcium homeostasis and alter physiologic functioning, resulting in significant clinical symptoms. A review of how the parathyroid glands and parathyroid hormone affect calcium balance and of the problems that result from altered function promotes a better appreciation of the important role played by these sometimes \u201cforgotten\u201d glands in maintaining normal neonatal physiologic functioning.<\/jats:p>","DOI":"10.1891\/0730-0832.19.1.9","type":"journal-article","created":{"date-parts":[[2012,5,8]],"date-time":"2012-05-08T07:40:02Z","timestamp":1336462802000},"page":"9-16","source":"Crossref","is-referenced-by-count":3,"title":["Parathyroids: The Forgotten Glands"],"prefix":"10.1891","volume":"19","author":[{"given":"Shari","family":"Steffensrud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2000,2,1]]},"reference":[{"key":"1","first-page":"145","volume-title":"Embryology","author":"JD Fix","year":"1995"},{"key":"2","first-page":"186","volume-title":"The Developing Human: Clinically Oriented Embryology","author":"KL Moore","year":"1993"},{"key":"3","first-page":"868","volume-title":"Textbook of Medical Physiology","author":"AC. Guyton","year":"1991"},{"key":"4","first-page":"655","article-title":"Agents that affect bone mineral homeostasis","volume-title":"Basic and Clinical Pharmacology","author":"DD. Bikle","year":"1995"},{"key":"5","first-page":"324","article-title":"Developmental endocrinology: Pharmacological aspects","volume-title":"Pediatric Pharmacology and Therapeutics","author":"FJ Holland","year":"1993"},{"key":"6","unstructured":"Bullock J, Boyle J III, and Wang MB. 1995. National Medical Series for Independent Study: <i>Physiology<\/i>, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 533\u2013539."},{"key":"7","first-page":"993","article-title":"Disorders of calcium homeostasis","volume-title":"Intensive Care of the Fetus and Neonate","author":"FR. Greer","year":"1996"},{"key":"8","first-page":"235","volume-title":"Physiology","author":"LS. Costanzo","year":"1995"},{"key":"9","first-page":"1463","article-title":"Disorders of calcium, phosphorus, and magnesium metabolism","volume-title":"Neonatal-Perinatal Medicine: Diseases of the Fetus and Newborn","author":"S Demarini","year":"1997"},{"issue":"3","key":"10","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1210\/endo-119-3-1406","article-title":"Parathyroid hormone stimulates calcium transport in perfused duodena from normal chicks: Comparison with the rapid (transcaltacheic) effect of 1,25-dihydroxyvitamin D3","volume":"119","author":"I Nemere","year":"1986","journal-title":"Endocrinology"},{"key":"11","first-page":"51","article-title":"Calcium and magnesium metabolism","volume-title":"CRC Handbook of Clinical Chemistry","volume":"4","author":"WWK Koo","year":"1989"},{"key":"12","first-page":"831","article-title":"Calcium, phosphorus, magnesium, and vitamin D","volume-title":"Neonatal Medicine","author":"J Senterre","year":"1987"},{"issue":"3","key":"13","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1210\/jcem-56-3-572","article-title":"Four-parameter model of the sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue","volume":"56","author":"EM. Brown","year":"1983","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"issue":"4","key":"14","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1210\/jcem-42-4-707","article-title":"Impaired release of parathyroid hormone in magnesium deficiency","volume":"42","author":"CS Anast","year":"1976","journal-title":"Journal of Endocrinology and Metabolism"},{"issue":"2","key":"15","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1152\/ajplegacy.1968.215.2.483","article-title":"Inhibition of parathyroid gland activity by hypermagnesemia","volume":"215","author":"HJ Gitelman","year":"1968","journal-title":"American Journal of Physiology"},{"issue":"5","key":"16","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1172\/JCI108582","article-title":"Inhibitory effects of hypermagnesemia on the renal action of parathyroid hormone","volume":"58","author":"E Slatopolsky","year":"1976","journal-title":"Journal of Clinical Investigation"},{"key":"17","first-page":"253","article-title":"Disorders of calcium and magnesium homeostasis","volume-title":"Neonatal Therapeutics","author":"ML Cruz","year":"1991"},{"issue":"4","key":"18","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1210\/jcem-47-4-800","article-title":"Parathyroid hormone secretion in magnesium deficiency","volume":"47","author":"R Rude","year":"1978","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"issue":"3","key":"19","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1365-2265.1976.tb01947.x","article-title":"Functional hypoparathyroidism and parathyroid hormone end-organ resistance in human magnesium deficiency","volume":"5","author":"R Rude","year":"1976","journal-title":"Clinical Endocrinology"},{"issue":"16","key":"20","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1056\/NEJM197004162821608","article-title":"Physiologic and pharmacologic regulation of bone resorption","volume":"282","author":"L Raisz","year":"1970","journal-title":"New England Journal of Medicine"},{"key":"21","first-page":"614","volume-title":"Maternal, Fetal, and Neonatal Physiology: A Clinical Perspective","author":"ST Blackburn","year":"1992"},{"key":"22","first-page":"387","article-title":"Neonatal hypocalcemia","volume-title":"Pediatric Endocrinology: A Clinical Guide","author":"WWK Koo","year":"1985"},{"key":"23","first-page":"351","article-title":"Human neonatal hypocalcemia","volume-title":"Perinatal Calcium and Phosphorus Metabolism","author":"L David","year":"1983"},{"issue":"2","key":"24","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1203\/00006450-199102000-00020","article-title":"Circulating levels of biologically active and immunoreactive intact parathyroid hormone in human newborns","volume":"29","author":"LP Rubin","year":"1991","journal-title":"Pediatric Research"},{"issue":"5","key":"25","first-page":"803","article-title":"Serum immunoreactive calcitonin in low birth weight infants: Description of early changes; effect of intravenous calcium infusion; relationships with early changes in serum calcium, phosphorus, magnesium, parathyroid hormone, and gastrin levels","volume":"15","author":"L David","year":"1981","journal-title":"Pediatric Research"},{"key":"26","first-page":"1189","article-title":"Disorders of calcium and phosphorus metabolism","volume-title":"Avery's Diseases of the Newborn","author":"LP. 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