{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T08:30:53Z","timestamp":1649147453810},"reference-count":12,"publisher":"Springer Publishing Company","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:p>The most severe manifestation of congenital ichthyosis presents itself in the form known as harlequin ichthyosis. Harlequin ichthyosis is characterized by a profound thickening of the fetal skin. Affected infants are born with a thick \u201chorny shell\u201d of dense, waxy, platelike scales with deep, irregular fissures covering the body. Contraction of the extremities is seen, along with deformities of the ears, eyes, mouth, and digits. This \u201carmor\u201d limits movement and compromises the skin\u2019s barrier defense, leaving the newborn at risk for metabolic abnormalities and infection. A case study of our unit\u2019s experience is provided.<\/jats:p>","DOI":"10.1891\/0730-0832.23.3.7","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T09:34:44Z","timestamp":1321436084000},"page":"7-12","source":"Crossref","is-referenced-by-count":2,"title":["Harlequin Ichthyosis: A Case Study"],"prefix":"10.1891","volume":"23","author":[{"given":"Laura","family":"Murphy-Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Vella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phyllis","family":"Lawlor-Klean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2004,5,1]]},"reference":[{"issue":"8","key":"1","first-page":"27","article-title":"Nursing a special patient: The infant with congenital ichthyosis\u2014harlequin syndrome.","volume":"9","author":"K DeMerchant","year":"1991","journal-title":"Neonatal Network"},{"issue":"3","key":"2","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1525-1470.1992.tb00358.x","article-title":"Harlequin fetus treated with etretinate.","volume":"9","author":"M. 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Ichthyosis fetalis. <i>E-medicine<\/i>, <a target=\"_blank\" href='www.emedicine.com\/derm\/topic192.htm'>www.emedicine.com\/derm\/topic192.htm<\/a>"},{"issue":"7","key":"5","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1046\/j.1365-4362.2001.01173.x","article-title":"Successful treatment of harlequin ichthyosis with acitetin.","volume":"40","author":"S Singh","year":"2001","journal-title":"Journal of Dermatology"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0923-1811(99)00024-9","article-title":"The pathogenesis of severe congenital ichthyosis of the neonate.","volume":"21","author":"M. Akiyama","year":"1999","journal-title":"Journal of Dermatological Science"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Shareef M, et al. 2000. Collodion baby: A case report. <i>Journal of Perinatology<\/i> 20(4): 267\u2013269.","DOI":"10.1038\/sj.jp.7200369"},{"issue":"4","key":"8","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0031-3955(16)38156-1","article-title":"All about ichthyosis.","volume":"38","author":"T Shwayder","year":"1991","journal-title":"Pediatric Clinics of North America"},{"issue":"3","key":"9","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1365-2133.1996.tb01512.x","article-title":"A longitudinal study of a harlequin infant presenting clinically as non-bullous congenital ichthyosiform erythroderma.","volume":"135","author":"M Haftek","year":"1996","journal-title":"British Journal of Dermatology"},{"key":"10","unstructured":"Paller AS. 2001. Disorders of cornification (ichthyosis). In <i>Textbook of Neonatal Dermatology<\/i>, Eichenfield LF, Frieden IJ, and Esterly NB, eds. Philadelphia: WB Saunders, 276\u2013293."},{"key":"11","unstructured":"American Medical Association. 1992. Treatment decisions for seriously ill newborns. Retrieved August 25, 2003, from <a target=\"_blank\" href='http:\/\/www.ama-assn.org\/ama\/pub\/category\/8460.html'>http:\/\/www.ama-assn.org\/ama\/pub\/category\/8460.html<\/a>"},{"issue":"5","key":"12","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1552-6909.2002.tb00076.x","article-title":"Against all odds: Breastfeeding a baby with harlequin ichthyosis.","volume":"31","author":"P Ripmeester","year":"2002","journal-title":"Journal of Obstetric, Gynecologic, and Neonatal Nursing"}],"container-title":["Neonatal Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1891\/0730-0832.23.3.7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T17:05:49Z","timestamp":1568826349000},"score":1,"resource":{"primary":{"URL":"http:\/\/connect.springerpub.com\/lookup\/doi\/10.1891\/0730-0832.23.3.7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2004,5,1]]},"published-print":{"date-parts":[[2004,5]]}},"alternative-id":["10.1891\/0730-0832.23.3.7"],"URL":"https:\/\/doi.org\/10.1891\/0730-0832.23.3.7","relation":{},"ISSN":["0730-0832","1539-2880"],"issn-type":[{"value":"0730-0832","type":"print"},{"value":"1539-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}