{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T06:30:08Z","timestamp":1690525808603},"reference-count":16,"publisher":"Springer Publishing Company","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:p>BRAIN TYPE NATRIURETIC PEPTIDE, also called B-type natriuretic peptide (BNP), has emerged as a valuable diagnostic and prognostic marker in the assessment of heart failure in adults.<jats:sup>1\u20137<\/jats:sup> Serum BNP levels have also been shown to differentiate pulmonary from cardiac causes of dyspnea and to be useful as a screening tool for ventricular hypertrophy, ventricular diastolic dysfunction, transplant rejection, and risk for sudden death in adult patients with congestive heart failure (CHF).<jats:sup>3,7,8<\/jats:sup> In pediatric patients, BNP levels have been found to increase with a hemodynamically significant ventricular septal defect and to correlate with the volume of the shunt and the left ventricular end diastolic volume.<jats:sup>7<\/jats:sup> Recently, BNP levels have been investigated for use in determining the hemodynamic significance of a patent ductus arteriosus (PDA) in preterm neonates.<jats:sup>3,7,9\u201311<\/jats:sup> They have also been studied for use in the diagnosis and management of persistent pulmonary hypertension in term and near-term infants.<jats:sup>6<\/jats:sup> This article reviews BNP terminology, structure, physiology, measurement, and potential utility in the NICU.<\/jats:p>","DOI":"10.1891\/0730-0832.27.5.343","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T09:41:41Z","timestamp":1321436501000},"page":"343-346","source":"Crossref","is-referenced-by-count":3,"title":["Brain Type Natriuretic Peptide"],"prefix":"10.1891","volume":"27","author":[{"given":"Patricia","family":"Nash","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2008,9,1]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1161\/01.CIR.0000016642.15031.34","article-title":"B-type natriuretic peptide predicts sudden death in patients with chronic heart failure.","volume":"105","author":"R. Berger","year":"2002","journal-title":"Circulation"},{"key":"2","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1161\/01.CIR.0000057608.97285.20","article-title":"Use of biomarkers in the management of heart failure: Are we there yet?","volume":"107","author":"B. Bozkurt","year":"2003","journal-title":"Circulation"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Flynn, P. A., DaGraca, R. L., Auld, P. A. M., Nesin, M, & Kleinman, C. S. (2005). The use of a bedside assay for plasma B-type natriuretic peptide as a biomarker in the management of patent ductus arteriosus in premature neonates. <i>The Journal of Pediatrics, 147<\/i>, 38\u201342.","DOI":"10.1016\/j.jpeds.2005.03.040"},{"key":"4","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1136\/heart.89.8.875","article-title":"Normal values of B type natriuretic peptide in infants, children, and adolescents.","volume":"89","author":"A. Koch","year":"2003","journal-title":"Heart"},{"key":"5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00246-003-0578-0","article-title":"Utility of B-type natriuretic peptide in differentiating congestive heart failure from lung disease in pediatric patients with respiratory distress.","volume":"25","author":"S. Koulouri","year":"2004","journal-title":"Pediatric Cardiology"},{"key":"6","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1542\/peds.2004-0525","article-title":"Brain-type natriuretic peptide in the diagnosis and management of persistent pulmonary hypertension of the newborn.","volume":"114","author":"E. Reynolds","year":"2004","journal-title":"Pediatrics"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Sanjeev, S., Pettersen, M., Lua, J., Thomas, R., Shankaran, S., & L'Ecuyer, T. L. (2005). Role of plasma B-type natriuretic peptide in screening for hemodynamically significant patent ductus arteriosus in preterm neonates. <i>Journal of Perinatology, 25<\/i>, 709\u2013713.","DOI":"10.1038\/sj.jp.7211383"},{"key":"8","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/j.1651-2227.2004.tb02984.x","article-title":"N-terminal pro-B-type natriuretic peptide: Reference plasma levels from birth to adolescence. Elevated levels at birth and in infants and children with heart disease.","volume":"93","author":"A. Nir","year":"2004","journal-title":"Acta Paediatrica"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Choi, B. M., Lee, K. H., Eun, B. L., Yoo, K. H., Hong, Y. S., Son, C. S., et al. (2005). Utility of rapid B-type natriuretic peptide assay for diagnosis of symptomatic patent ductus arteriosus in preterm infants. <i>Pediatrics, 115<\/i>, e255\u2013e261.","DOI":"10.1542\/peds.2004-1837"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Holmstrom, H., Hall, C., & Thaulow, E. (2001). Plasma levels of natriuretic peptides and hemodynamic assessment of patent ductus arteriosus in preterm infants. <i>Acta Paediatrica, 90<\/i>, 184\u2013191.","DOI":"10.1111\/j.1651-2227.2001.tb00282.x"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Puddy, V. F., Amirmansour, C., Williams, A. F., & Singer, D. R. J. (2002). Plasma brain natriuretic peptide as a predictor of haemodynamically significant patent ductus arteriosus in preterm infants. <i>Clinical Science, 103<\/i>, 75\u201377.","DOI":"10.1042\/cs1030075"},{"key":"12","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1542\/peds.112.4.896","article-title":"Plasma concentrations of aminoterminal pro atrial natriuretic peptide and aminoterminal pro brain natriuretic peptide in healthy neonates: Marked and rapid increase after birth.","volume":"112","author":"T. Mir","year":"2003","journal-title":"Pediatrics"},{"key":"13","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0735-1097(01)01744-2","article-title":"Utility of a rapid B-natriuretic peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea.","volume":"39","author":"L. Morrison","year":"2002","journal-title":"Journal of the American College of Cardiology"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Sudoh, T., Minamino, N., Kangawa, K., Matsuo, H. (1988). Brain nitriuretic peptide-32: N-terminal six amino acid extended form of brain natriuretic peptide identified in porcine brain. <i>Biochemical and Biophysical Research Communications, 15<\/i>, 726\u2013732.","DOI":"10.1016\/S0006-291X(88)80555-2"},{"key":"15","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0378-3782(96)01741-0","article-title":"Early changes in plasma brain and atrial natriuretic peptides in premature infants: Correlation with pulmonary arterial pressure.","volume":"46","author":"Y. Ikemoto","year":"1996","journal-title":"Early Human Development"},{"key":"16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jacc.2003.07.037","article-title":"Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy.","volume":"43","author":"H. Yamaguchi","year":"2004","journal-title":"Journal of the American College of Cardiology"}],"container-title":["Neonatal Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1891\/0730-0832.27.5.343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T14:14:18Z","timestamp":1568816058000},"score":1,"resource":{"primary":{"URL":"http:\/\/connect.springerpub.com\/lookup\/doi\/10.1891\/0730-0832.27.5.343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2008,9,1]]},"published-print":{"date-parts":[[2008,9]]}},"alternative-id":["10.1891\/0730-0832.27.5.343"],"URL":"https:\/\/doi.org\/10.1891\/0730-0832.27.5.343","relation":{},"ISSN":["0730-0832","1539-2880"],"issn-type":[{"value":"0730-0832","type":"print"},{"value":"1539-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}