{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:25:51Z","timestamp":1758633951571},"reference-count":38,"publisher":"Springer Publishing Company","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:p>Retinopathy of prematurity (ROP) results from the abnormal growth of blood vessels in the vascular bed supporting the developing retina. Estimated to cause up to 500 new cases of blindness in the U.S. each year, ROP affects primarily infants born at less than 1,500 g. Although its etiology is not well understood, ROP is thought to occur as a result of a complex interaction between oxygen and vascular growth factors. This article briefly reviews the history of ROP, discusses its pathophysiology, and addresses the risk factors and strategies for prevention.<\/jats:p>","DOI":"10.1891\/0730-0832.28.2.93","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T14:43:43Z","timestamp":1321454623000},"page":"93-101","source":"Crossref","is-referenced-by-count":9,"title":["Retinopathy of Prematurity: An Eye Toward Better Outcomes"],"prefix":"10.1891","volume":"28","author":[{"given":"Charlene","family":"Pollan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2009,3,1]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/sj.jp.7211067","article-title":"Retinopathy of prematurity and pulse oximetry: A national survey of recent practices.","volume":"24","author":"C. Anderson","year":"2004","journal-title":"Journal of Perinatology"},{"key":"2","volume-title":"Baby ER","author":"E. Humes","year":"2000"},{"key":"3","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1136\/bjo.86.6.696","article-title":"Retinopathy of prematurity: Recent advances in our understanding.","volume":"86","author":"D. Wheatley","year":"2002","journal-title":"The British Journal of Ophthalmology"},{"key":"4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1172\/JCI200319093","article-title":"Preventing pathological regression of blood vessels.","volume":"112","author":"E. Keshet","year":"2003","journal-title":"The Journal of Clinical Investigation"},{"key":"5","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0161-6420(91)32074-8","article-title":"Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.","volume":"98","author":"E. Palmer","year":"1991","journal-title":"Ophthalmology"},{"key":"6","article-title":"Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation.","volume":"84","author":"W. Tin","year":"2001","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"key":"7","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/sj.jp.7211040","article-title":"Arterial oxygen fluctuation and retinopathy of prematurity in very-low-birth-weight infants.","volume":"24","author":"J. York","year":"2004","journal-title":"Journal of Perinatology"},{"key":"8","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1542\/peds.111.2.339","article-title":"Can changes in clinical practice decrease the incidence of severe retinopathy of prematurity in very low birth weight infants?","volume":"111","author":"L. 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Coalson","year":"2006","journal-title":"Seminars in Perinatology"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Castillo, A., Sola, A., Baquero, H., Neira, F., Ramiro, A., Deulofeut, R., et al. (2008). Pulse oxygen saturation levels and arterial oxygen tension values in newborns receiving oxygen therapy in the neonatal intensive care unit: Is 85% to 93% an acceptable range? <i>Pediatrics, 121<\/i>, 882\u2013889.","DOI":"10.1542\/peds.2007-0117"},{"key":"17","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1056\/NEJMoa023080","article-title":"Oxygen-saturation targets and outcomes in extremely preterm infants.","volume":"349","author":"L. Askie","year":"2003","journal-title":"The New England Journal of Medicine"},{"key":"18","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1053\/j.semperi.2006.05.003","article-title":"Pathogenesis of bronchopulmonary dysplasia.","volume":"30","author":"P. 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Johnson","year":"1985","journal-title":"Pediatrics"},{"key":"22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1159\/000027482","article-title":"Risk factors in retinopathy of prematurity. A multivariate statistical analysis.","volume":"214","author":"V. Seiberth","year":"2000","journal-title":"Ophthalmologica"},{"key":"23","first-page":"907","article-title":"The eye in childhood.","volume":"60","author":"M. Mills","year":"1999","journal-title":"The American Academy of Family Physicians"},{"key":"24","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1365-3016.2003.00545.x","article-title":"Postnatal risk factors of retinopathy of prematurity.","volume":"18","author":"T. 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The design of the multicenter study of light reduction in retinopathy of prematurity (LIGHT-ROP). <i>Journal of Pediatric Ophthalmology and Strabismus, 36<\/i>, 257\u2013263."},{"key":"29","doi-asserted-by":"crossref","unstructured":"Primhak, R. (2001). Oxygen saturation and retinopathy of prematurity. [Letters to the editor]. <i>Archives of Disease in Childhood. Fetal and Neonatal Edition, 85<\/i>, F75.","DOI":"10.1136\/fn.85.1.F75"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Roberton, N. (2001). Two sacred cows of neonatal intensive care. [Letters to the editor]. <i>Archives of Disease in Childhood. Fetal and Neonatal Edition, 85<\/i>, F75\u2013F76.","DOI":"10.1136\/fn.85.1.F75b"},{"key":"31","unstructured":"Marlow, N. (2001). High or low oxygen saturation for the preterm baby. <i>Archives of Disease in Childhood. Fetal and Neonatal Edition, 84<\/i>, F149."},{"key":"32","doi-asserted-by":"crossref","unstructured":"STOP-ROP Multicenter Study Group. (2000). 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