{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:40:33Z","timestamp":1760042433869},"reference-count":46,"publisher":"Springer Publishing Company","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2010,3]]},"abstract":"Septicemia, one of the major causes of morbidity and mortality in the neonatal period, often has a rapid and fulminant course. Low-birth-weight infants with persistentStaphylococcus aureus<\/jats:italic>septicemia, possibly associated with percutaneous central venous catheters, may develop metastatic infections including endocarditis with large vegetations. This article describes a neonate withS. aureus<\/jats:italic>bacteremia that resolved with treatment who died secondary to decreased left ventricular function. At autopsy, organizing microthrombi were seen within both atria, the left ventricle, and the left coronary arterial system. Extensive infarcts were noted throughout the entire myocardium of the left ventricle. It was suspected, but not proven, that the thrombotic sequelae from septicemia caused this neonate\u2019s death.<\/jats:p>","DOI":"10.1891\/0730-0832.29.2.75","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T14:39:53Z","timestamp":1321454393000},"page":"75-85","source":"Crossref","is-referenced-by-count":2,"title":["Staphylococcus aureus<\/i>Septicemia with a Fatal Transmural Myocardial Infarction in a 27-Week-Gestation Twin Infant: A Case Study"],"prefix":"10.1891","volume":"29","author":[{"given":"Amanda","family":"Hines","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Rawlins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2010,3,1]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.clp.2007.11.014","article-title":"Hospital-acquired infections in the NICU: Epidemiology for the new millennium.","volume":"35","author":"A. Carey","year":"2008","journal-title":"Clinics in Perinatology"},{"key":"2","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0022-3476(96)70254-8","article-title":"Volume of blood required to detect common neonatal pathogens.","volume":"129","author":"R. Schelonka","year":"1996","journal-title":"The Journal of Pediatrics"},{"key":"3","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1128\/JCM.24.3.353-356.1986","article-title":"Volume of blood submitted for cultures from neonates.","volume":"24","author":"P. Neal","year":"1986","journal-title":"Journal of Clinical Microbiology"},{"key":"4","first-page":"551","article-title":"Bacterial sepsis and meningitis","volume-title":"Avery's diseases of the newborn","author":"H. Taeusch","year":"2005"},{"issue":"1","key":"5","first-page":"1","article-title":"Coagulase negative staphylococcal sepsis with upper extremity gangrene and shock in a premature infant: An unusual complication of a peripheral intravenous catheter.","volume":"5","author":"B. Bengt-Ola","year":"2005","journal-title":"Internet Journal of Pediatrics and Neonatology"},{"key":"6","unstructured":"Todar, K. (2005). Staphylococcus. Todar's online textbook of bacteriology<\/i>, (pp. 1\u201311). Retrieved February 2010, from www.textbookofbacteriology.net\/staph.html<\/a>"},{"key":"7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ajic.2006.09.016","article-title":"Morbidity and mortality of staphylococcal bacteremia in children.","volume":"35","author":"H. Hakim","year":"2007","journal-title":"American Journal of Infection Control"},{"key":"8","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1086\/503337","article-title":"Incidence of pediatric and neonatal intensive care unit\u2013acquired infections.","volume":"27","author":"S. Banerjee","year":"2006","journal-title":"Infection Control and Hospital Epidemiology"},{"key":"9","doi-asserted-by":"crossref","unstructured":"National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1992 through June 2004, issued October 2004. American Journal of Infection Control, 32<\/i>, 470\u2013485.","DOI":"10.1016\/j.ajic.2004.10.001"},{"key":"10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/sj.jp.7210660","article-title":"\"Proactive\" management of percutaneously inserted central catheters results in decreased incidence of infection in the ELBW population.","volume":"22","author":"S. Golombek","year":"2002","journal-title":"Journal of Perinatology"},{"key":"11","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1097\/01.inf.0000095429.97172.48","article-title":"Role of antimicrobial applications to the umbilical cord in neonates to prevent bacterial colonization and infection: A review of the evidence.","volume":"22","author":"L. Mullany","year":"2003","journal-title":"Pediatric Infectious Disease Journal"},{"key":"12","first-page":"53","article-title":"Prevention of the colonization of the nasal cavity in newborn infants by hospital strains of Staphylococcus aureus using lactic acid bacteria.","volume":"1","author":"A. Ambartsumian","year":"1984","journal-title":"Zhurnal Mikrobiologii, Epidemiologii, I Immunobiologii"},{"key":"13","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.clp.2004.11.005","article-title":"Intravascular catheter complications in the neonatal intensive care unit.","volume":"32","author":"M. Hermansen","year":"2005","journal-title":"Clinics in Perinatology"},{"key":"14","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1080\/pdp.21.1.75.78","article-title":"Pathology teach and tell: Neonatal infective endocarditis.","volume":"21","author":"N. Kakkar","year":"2002","journal-title":"Pediatric Pathology & Molecular Medicine"},{"key":"15","first-page":"345","article-title":"Bacterial endocarditis in neonatal intensive care.","volume":"35","author":"G. Opie","year":"1999","journal-title":"Journal of Pediatric Child Health"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Valente, A. M., Jain, R., Scheurer, M., Fowler, V. G., Jr., Corey, G. R., Bengur, A. R., et al. (2005). Frequency of infective endocarditis among infants and children with Staphylococcus aureus<\/i> bacteremia. Pediatrics, 115<\/i>, e15\u2013e19.","DOI":"10.1542\/peds.2004-1152"},{"key":"17","volume-title":"Neonatal-perinatal medicine: Diseases of the fetus and infant","volume":"2","author":"A. Fanaroff","year":"2006"},{"key":"18","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/j.1651-2227.2008.00864.x","article-title":"Removal of percutaneously inserted central venous catheters in neonates is associated with the occurrence of sepsis.","volume":"9","author":"A. Van den Hoogen","year":"2008","journal-title":"Acta Paediatrica"},{"key":"19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/sj.jp.7211655","article-title":"Catheter related bloodstream infections following PICC removal in preterm infants.","volume":"27","author":"R. Brooker","year":"2007","journal-title":"Journal of Perinatology"},{"key":"20","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1542\/peds.2007-1962","article-title":"Percutaneously inserted central catheter for total parenteral nutrition in neonates: Complication rates related to upper versus lower extremity insertion.","volume":"121","author":"V. Hoang","year":"2008","journal-title":"Pediatrics"},{"key":"21","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1067\/mpd.2001.118192","article-title":"Venous thromboembolism in childhood: A prospective two-year registry in The Netherlands.","volume":"139","author":"C. van Ommen","year":"2001","journal-title":"The Journal of Pediatrics"},{"key":"22","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/j.1540-8175.2005.03107.x","article-title":"Association of prothrombin gene mutation with sepsis in a preterm with multiple intracardiac thrombi.","volume":"22","author":"A. Cinar","year":"2005","journal-title":"Echocardiography"},{"key":"23","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1055\/s-0038-1651626","article-title":"Do coagulation screening tests detect increased generation of thrombin and plasmin in sick newborn infants?","volume":"69","author":"B. Schmidt","year":"1993","journal-title":"Thrombosis and Haemostasis"},{"key":"24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1017\/S1047951106000436","article-title":"Intra-atrial thrombus in a neonate with coarctation of the aorta.","volume":"16","author":"K. Al Dhahri","year":"2006","journal-title":"Cardiology in the Young"},{"key":"25","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1542\/peds.109.1.153","article-title":"Infective endocarditis successfully treated in extremely low birth weight infants with recombinant tissue plasminogen activator.","volume":"109","author":"K. Marks","year":"2002","journal-title":"Pediatrics"},{"issue":"5","key":"26","first-page":"1","article-title":"Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates.","volume":"88","author":"F. Tardin","year":"2007","journal-title":"Arquivos brasileiros de Cardiologia"},{"key":"27","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1067\/mpd.2001.118428","article-title":"Safety and outcomes of thrombolysis with tissue plasminogen activator for treatment of vascular thrombosis in children","volume":"139","author":"A. Gupta","year":"2001","journal-title":"The Journal of Pediatrics"},{"key":"28","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0022-3476(98)70036-8","article-title":"Successful treatment of a staphylococcal endocarditis vegetation with tissue plasminogen activator.","volume":"132","author":"R. Fleming","year":"1998","journal-title":"The Journal of Pediatrics"},{"key":"29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/15513810601015605","article-title":"Intrauterine myocardial infarction: Unsuspected diagnosis in the delivery room.","volume":"25","author":"A. Concheiro-Guis\u00e1n","year":"2006","journal-title":"Fetal and Pediatric Pathology"},{"key":"30","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1136\/hrt.2006.102632","article-title":"Atrial infarction in a premature infant.","volume":"93","author":"M. Calabr\u00f2","year":"2007","journal-title":"Heart"},{"key":"31","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1651-2227.2007.00104.x","article-title":"Is serum troponin T a useful marker of myocardial damage in newborn infants with perinatal asphyxia?","volume":"96","author":"S. Costa","year":"2007","journal-title":"Acta Paediatrica"},{"key":"32","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/s004310051192","article-title":"Myocardial ischaemia in neonates with perinatal asphyxia: Electrocardiographic, echocardiographic and enzymatic correlations.","volume":"158","author":"I. Barberi","year":"1999","journal-title":"European Journal of Pediatrics"},{"key":"33","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000089795","article-title":"Cardiac troponin I in asphyxiated neonates.","volume":"89","author":"D. Trevisanuto","year":"2006","journal-title":"Biology of the Neonate"},{"key":"34","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1017\/S1047951100008428","article-title":"Thrombotic occlusion of the main stem of the left coronary artery in the neonate.","volume":"9","author":"L. Abdurrahman","year":"1999","journal-title":"Cardiology in the Young"},{"key":"35","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/14767050500324669","article-title":"Neonatal myocardial infarction due to thrombotic occlusion.","volume":"19","author":"M. Takeuchi","year":"2006","journal-title":"The Journal of Maternal-Fetal & Neonatal Medicine"},{"key":"36","doi-asserted-by":"crossref","DOI":"10.1136\/fn.85.2.F137","article-title":"Paradoxical embolism causing fatal myocardial infarction in a newborn infant.","volume":"85","author":"A. Tillett","year":"2001","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"key":"37","first-page":"519","article-title":"The cardiovascular system","volume-title":"Pediatric pathology","author":"K. Patterson","year":"2001"},{"key":"38","doi-asserted-by":"crossref","DOI":"10.1136\/adc.2002.025478","article-title":"Concentrations of cardiac troponin T in neonates with and without respiratory distress.","volume":"89","author":"S. Clark","year":"2004","journal-title":"Archives of Disease in Childhood. Fetal and Neonatal Edition"},{"key":"39","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1017\/S1047951100013068","article-title":"Acute myocardial infarction in the neonatal period.","volume":"12","author":"S. Murugan","year":"2002","journal-title":"Cardiology in the Young"},{"key":"40","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.clinbiochem.2004.08.003","article-title":"Reference values for cardiac troponins T and I in healthy neonates.","volume":"37","author":"H. Baum","year":"2004","journal-title":"Clinical Biochemistry"},{"key":"41","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1080\/08035250510041222","article-title":"Troponin-T levels in perinatally asphyxiated infants during the first 15 days of life.","volume":"94","author":"T. Gunes","year":"2005","journal-title":"Acta Paediatrica"},{"key":"42","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1136\/hrt.2005.071282","article-title":"Differential diagnosis of elevated troponins.","volume":"92","author":"S. Korff","year":"2006","journal-title":"Heart"},{"key":"43","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000084067","article-title":"Usefulness of cardiac troponin T and echocardiography in the diagnosis of hypoxic myocardial injury of full-term neonates.","volume":"88","author":"M. Szymankiewicz","year":"2005","journal-title":"Biology of the Neonate"},{"key":"44","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00431-005-0001-3","article-title":"Sequential cardiac troponin T following delivery and its relationship with myocardial performance in neonates with respiratory distress syndrome.","volume":"165","author":"S. Clark","year":"2006","journal-title":"European Journal of Pediatrics"},{"key":"45","doi-asserted-by":"crossref","unstructured":"Armstrong, D., Battin, M. R., Knight, D., & Skinner, J. (2002). Staphylococcus aureus<\/i> endocarditis in the preterm neonate. American Journal of Perinatology, 19<\/i>, 247\u2013251.","DOI":"10.1055\/s-2002-33087"},{"key":"46","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00383-003-1090-6","article-title":"An epidemic of isolated perforation: How can we stop it?","volume":"20","author":"J. Hutson","year":"2004","journal-title":"Pediatric Surgery International"}],"container-title":["Neonatal Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1891\/0730-0832.29.2.75","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T19:27:04Z","timestamp":1639682824000},"score":1,"resource":{"primary":{"URL":"http:\/\/connect.springerpub.com\/lookup\/doi\/10.1891\/0730-0832.29.2.75"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":46,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2010,3,1]]},"published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.1891\/0730-0832.29.2.75"],"URL":"https:\/\/doi.org\/10.1891\/0730-0832.29.2.75","relation":{},"ISSN":["0730-0832","1539-2880"],"issn-type":[{"value":"0730-0832","type":"print"},{"value":"1539-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}