{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:54:54Z","timestamp":1762001694168},"reference-count":19,"publisher":"Springer Publishing Company","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatal Network"],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neonatal osteomyelitis is a rare and challenging diagnosis, particularly in the early onset period. Neonatal osteomyelitis is predominantly caused by<jats:italic>Staphylococcus aureus<\/jats:italic>with single bone involvement. Here, we report two cases of neonatal osteomyelitis in premature infants caused by<jats:italic>Klebsiella pneumoniae<\/jats:italic>with multiple bone lesions. Both cases presented with sepsis and meningitis and were initially diagnosed by incidental findings on plain films, with follow-up bone scan imaging. In both cases, diagnosis was timely and treatment was successful. These cases highlight the need to include neonatal osteomyelitis in the differential diagnosis when late-onset or prolonged neonatal sepsis is present, particularly because long-term outcome is dependent on rapid diagnosis and initiation of treatment.<\/jats:p>","DOI":"10.1891\/0730-0832.30.2.81","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T14:41:32Z","timestamp":1321454492000},"page":"81-88","source":"Crossref","is-referenced-by-count":5,"title":["Gram-Negative Neonatal Osteomyelitis: Two Case Reports"],"prefix":"10.1891","volume":"30","author":[{"given":"Jinping","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2011,1,1]]},"reference":[{"key":"2019091812250586000_30.2.81.1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0891-5520(20)30428-1","article-title":"Osteomyelitis in the neonate","volume":"6","year":"1992","journal-title":"Infectious Disease Clinics of North America"},{"issue":"5","key":"2019091812250586000_30.2.81.2","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00006454-198309000-00018","article-title":"Infections of lymph nodes of the head and neck","volume":"2","year":"1983","journal-title":"Pediatric Infectious Disease"},{"issue":"5","key":"2019091812250586000_30.2.81.3","first-page":"846","article-title":"Neonatal osteomyelitis","volume":"72","year":"1990","journal-title":"The Journal of Bone and Joint Surgery"},{"key":"2019091812250586000_30.2.81.4","doi-asserted-by":"publisher","DOI":"10.1891\/0730-0832.21.1.9"},{"key":"2019091812250586000_30.2.81.5","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.10_Spec_No.1060"},{"key":"2019091812250586000_30.2.81.6","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200202000-00020"},{"key":"2019091812250586000_30.2.81.7","doi-asserted-by":"publisher","DOI":"10.1007\/BF01954084"},{"key":"2019091812250586000_30.2.81.8","first-page":"129","article-title":"Methicillin-resistant Staphylococcus aureus osteomyelitis and septic arthritis in neonates: Diagnosis and management","volume":"60","year":"2007","journal-title":"Japanese Journal of Infectious Diseases"},{"issue":"39\u201340","key":"2019091812250586000_30.2.81.9","first-page":"575","article-title":"Diagnosis of acute haematogenous osteomyelitis and septic arthritis: 20 years experience at the University Children\u2019s Hospital Basel","volume":"131","year":"2001","journal-title":"Swiss Medical Weekly"},{"key":"2019091812250586000_30.2.81.10","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000143658.74006.d0"},{"key":"2019091812250586000_30.2.81.11","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199512000-00004"},{"key":"2019091812250586000_30.2.81.12","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200306000-00020"},{"key":"2019091812250586000_30.2.81.13","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-200008000-00008"},{"key":"2019091812250586000_30.2.81.14","doi-asserted-by":"publisher","DOI":"10.1097\/01.pec.0000190226.12610.24"},{"key":"2019091812250586000_30.2.81.15","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.165.2.7618566"},{"key":"2019091812250586000_30.2.81.16","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3400"},{"key":"2019091812250586000_30.2.81.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2005.02.005"},{"key":"2019091812250586000_30.2.81.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2006.09.009"},{"key":"2019091812250586000_30.2.81.19","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3181ab472d"}],"container-title":["Neonatal Network"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1891\/0730-0832.30.2.81","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T19:27:16Z","timestamp":1639682836000},"score":1,"resource":{"primary":{"URL":"http:\/\/connect.springerpub.com\/lookup\/doi\/10.1891\/0730-0832.30.2.81"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":19,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,1,1]]},"published-print":{"date-parts":[[2011]]}},"alternative-id":["10.1891\/0730-0832.30.2.81"],"URL":"https:\/\/doi.org\/10.1891\/0730-0832.30.2.81","relation":{},"ISSN":["0730-0832","1539-2880"],"issn-type":[{"value":"0730-0832","type":"print"},{"value":"1539-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}