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All English language articles published since 2005 in PubMed and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) were analyzed for existing evidence-based methods for whole body cooling. Whole body cooling is effective in the treatment of HIE in term and near-term neonates. Further research is needed to investigate the use of adjunctive therapies in conjunction with whole body cooling for improved neuroprotection.<\/jats:p>","DOI":"10.1891\/0730-0832.36.5.273","type":"journal-article","created":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T03:05:44Z","timestamp":1503975944000},"page":"273-279","source":"Crossref","is-referenced-by-count":6,"title":["The Use of Whole Body Cooling in the Treatment of Hypoxic-Ischemic Encephalopathy"],"prefix":"10.1891","volume":"36","author":[{"given":"Tiffany","family":"Harriman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanda T.","family":"Bradshaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Blake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2017,1,1]]},"reference":[{"key":"2019091815450818000_36.5.273.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.05.010"},{"key":"2019091815450818000_36.5.273.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.02.003"},{"key":"2019091815450818000_36.5.273.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315788"},{"issue":"3","key":"2019091815450818000_36.5.273.4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.clp.2016.04.002","article-title":"Pathophysiology of birth asphyxia","volume":"43","year":"2016","journal-title":"Clin Perinatol"},{"key":"2019091815450818000_36.5.273.5","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/479135"},{"issue":"3","key":"2019091815450818000_36.5.273.6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/j.nainr.2011.07.004","article-title":"Hypoxic ischemic encephalopathy: pathophysiology and experimental treatments","volume":"11","year":"2011","journal-title":"Newborn Infant Nurs Rev"},{"key":"2019091815450818000_36.5.273.7","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1976.00500100030012"},{"key":"2019091815450818000_36.5.273.8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2441"},{"key":"2019091815450818000_36.5.273.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcps050929"},{"key":"2019091815450818000_36.5.273.10","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000445580.65983.d2"},{"issue":"4","key":"2019091815450818000_36.5.273.11","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/jp.2014.190","article-title":"Short-term outcomes after perinatal hypoxic ischemic encephalopathy: a report from the Children\u2019s Hospital Neonatal Consortium HIE focus group","volume":"35","year":"2015","journal-title":"J Perinatol"},{"key":"2019091815450818000_36.5.273.12","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jpeds.2010.11.003","article-title":"Interruption of placental blood flow during labor: potential systemic and cerebral organ consequences","volume":"158","year":"2011","journal-title":"J Pediatr"},{"issue":"9","key":"2019091815450818000_36.5.273.13","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.earlhumdev.2015.06.008","article-title":"Serum calcium concentrations and incidence of hypocalcemia in infants with moderate or severe hypoxic-ischemic encephalopathy: effect of therapeutic hypothermia","volume":"91","year":"2015","journal-title":"Early Hum Dev"},{"key":"2019091815450818000_36.5.273.14","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-1566"},{"key":"2019091815450818000_36.5.273.15","doi-asserted-by":"crossref","unstructured":"Jacobs SE , Berg M , Hunt R , Tarnow-Mordi WO , Inder TE , Davis PG . Cooling for newborns with hypoxic ischaemic encephalopathy. 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Therapeutic hypothermia. In: Gomella T , Cunningham M , Eyal F , eds. Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs. 7th ed. 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