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Among affected infants, those with symptomatic comorbidities incur a significantly higher morbidity and mortality risk. Prompt identification and diagnosis of ACM, as well as evidence-based postnatal and postsurgical nursing and medical care, is critical. Early surgical intervention can repair an existing MMC and restore proper cerebrospinal fluid circulation, which can dramatically improve patient outcomes and quality of life, and reduce disease and health care burden.<\/jats:p>","DOI":"10.1891\/11-t-704","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T19:25:20Z","timestamp":1631561120000},"page":"313-320","source":"Crossref","is-referenced-by-count":13,"title":["Arnold-Chiari Malformation: Core Concepts"],"prefix":"10.1891","volume":"40","author":[{"given":"Kristina","family":"Fons","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"Jnah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2021,9,13]]},"reference":[{"key":"2021091312251313000_40.5.313.1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22442"},{"key":"2021091312251313000_40.5.313.2","doi-asserted-by":"crossref","unstructured":"Rorke-Adams LB . 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