{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T02:06:09Z","timestamp":1788833169866,"version":"build-2803163510"},"reference-count":61,"publisher":"Springer Publishing Company","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Res Theory Nurs Pract"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> The heel-lance (HL) method for blood collection from the newborn is controversial for the pain it causes. This is the first randomized controlled trial on the management and reduction of pain using the music of Wolfgang Amadeus Mozart (\u201cSonata K. 448\u201d) in premature infants hospitalized in a neonatal intensive care unit (NICU). This study has compared nonpharmacological techniques with standard procedure for reducing pain during HL procedure. <jats:bold>Methods:<\/jats:bold> Thirty-five premature infants were enrolled, each for 3 HL procedures, of which each was randomized to 1 of the 3 study arms. Arms were then compared in terms of the Premature Infant Pain Profile (PIPP) changes by analysis of variance (ANOVA). <jats:bold>Results:<\/jats:bold> One hundred five HL procedures were available for analysis (35 standard procedure, 35 music, 35 glucose). Median baseline PIPP was 3, and median PIPP after the HL procedure was 5. PIPP scale change was +3 in the control arm, +1 in the glucose arm, +2 in the music arm (<jats:italic>p<\/jats:italic> = .008). <jats:bold>Discussion:<\/jats:bold> Both glucose and music were safe and effective in limiting pain increase when compared to standard procedure in HL procedures in preterm infants.<\/jats:p>","DOI":"10.1891\/1541-6577.28.4.335","type":"journal-article","created":{"date-parts":[[2014,12,15]],"date-time":"2014-12-15T23:21:12Z","timestamp":1418685672000},"page":"335-348","source":"Crossref","is-referenced-by-count":36,"title":["Nonpharmacological Techniques to Reduce Pain in Preterm Infants Who Receive Heel-Lance Procedure: A Randomized Controlled Trial"],"prefix":"10.1891","volume":"28","author":[{"given":"Piera","family":"Bergomi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Chieppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Maini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Mugnos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Spotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrisoulle","family":"Tzialla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigia","family":"Scudeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"793","published-online":{"date-parts":[[2014,1,1]]},"reference":[{"key":"2019091917353570000_28.4.335.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2277"},{"issue":"3","key":"2019091917353570000_28.4.335.2","first-page":"55","article-title":"The well-being of the newborn infant in neonatal intensive care","volume":"62","year":"2010","journal-title":"Minerva Pediatrica"},{"issue":"3","key":"2019091917353570000_28.4.335.3","first-page":"183","article-title":"Music therapy intervention in the neonatal intensive care unit environment","volume":"87","year":"2011","journal-title":"Jornal De Pediatria"},{"key":"2019091917353570000_28.4.335.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.0730-7659.2006.00090.x"},{"key":"2019091917353570000_28.4.335.5","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.4.e49"},{"issue":"5","key":"2019091917353570000_28.4.335.6","first-page":"392","article-title":"Prevencion del dolor en recien nacidos de termino: Estudio aleatorizado sobre tres metodos","volume":"106","year":"2008","journal-title":"Archivos Argentinos De Pediatria"},{"key":"2019091917353570000_28.4.335.7","unstructured":"Bourdon A. (2010). Johann Christian Bach\u2019s influence on Mozart\u2019s developing style (Honors Thesis in Department of Music University of Richmond, VA). Retrieved from https:\/\/dspace.lasrworks.org\/bitstream\/handle\/10349\/915\/10mus-bourdonaustin.pdf?sequence=1"},{"key":"2019091917353570000_28.4.335.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2010.01.001"},{"key":"2019091917353570000_28.4.335.9","unstructured":"Carter G. (2008). Piano book: Pianos, composers, pianists, recording artists, repertoire, performing practice, analysis, expression, interpretation. 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