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Meningitis remains the most common and serious complication associated with late onset disease, occurring in 30 percent of cases. The assessment of risk for neonatal GBS infection should not be limited to the birth process or maternal screening results and intrapartum antibiotic prophylaxis treatment status. Horizontal transmission after birth from mothers, caregivers, and community sources has been observed. Late-onset GBS disease and its sequelae remain a significant risk to neonates, and clinicians should be able to recognize the signs and symptoms to provide timely antibiotic therapy. This article discusses of the pathogenesis, risk factors, clinical manifestations, diagnostics, and treatment of neonatal late-onset GBS infection and identifies implications for practicing clinicians.<\/jats:p>","DOI":"10.1891\/nn.2022-0027","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T04:45:11Z","timestamp":1680237911000},"page":"81-87","source":"Crossref","is-referenced-by-count":0,"title":["Not Just an Intrapartum Problem: Late-Onset Group B Streptococcus Disease"],"prefix":"10.1891","volume":"42","author":[{"given":"Lauren H.","family":"Lucas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary T.","family":"Earp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Bauserman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"793","published-online":{"date-parts":[[2023,3,3]]},"reference":[{"key":"2023033021450498000_42.2.81.1","doi-asserted-by":"crossref","unstructured":"Freudenhammer M , Karampatsas K ., Le Doare K ., et al. 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