{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:45:14Z","timestamp":1770219914466,"version":"3.49.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: A sensory ataxic neuropathy has been observed in Swedish Golden Retrievers recently.<\/jats:p>\n                  <jats:p>Animals: Twenty-one affected Golden Retrievers.<\/jats:p>\n                  <jats:p>Methods: Clinical and neurologic status, electrophysiologic, and pathologic status as well as pedigree analyses were evaluated.<\/jats:p>\n                  <jats:p>Results: Clinical signs had an insidious onset between 2 and 8 months of age and a slowly progressive course. Affected dogs were ataxic and dysmetric. They had abnormal postural reactions and decreased spinal reflexes but no apparent muscle atrophy. Clinical pathology, radiography, and electrophysiology of motor systems were all within reference values. Sensory nerve conduction results of affected dogs were significantly different from those of a group of control dogs. Necropsy revealed a chronic progressive central and peripheral sensorimotor axonopathy; the proprioceptive pathways were most severely affected.<\/jats:p>\n                  <jats:p>Conclusions and Clinical Importance: This disease in these Golden Retrievers is distinct from other canine breed-related neurodegenerative diseases or hereditary neurodegenerative diseases described in humans. Pedigree analyses indicated a hereditary background, but the mode of inheritance could not be established.<\/jats:p>","DOI":"10.1111\/j.1939-1676.2007.tb01953.x","type":"journal-article","created":{"date-parts":[[2010,3,11]],"date-time":"2010-03-11T08:04:32Z","timestamp":1268294672000},"page":"1307-1315","source":"Crossref","is-referenced-by-count":13,"title":["A Neurologic Syndrome in Golden Retrievers Presenting as a Sensory Ataxic Neuropathy"],"prefix":"10.1093","volume":"21","author":[{"given":"K Hultin","family":"J\u00e4derlund","sequence":"first","affiliation":[{"name":"Swedish University of Agricultural Sciences Department of Clinical Sciences, , Uppsala,","place":["Sweden"]},{"name":"Norwegian School of Veterinary Science Department of Companion Animal Clinical Sciences, , Oslo,","place":["Norway"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"\u00d6rvind","sequence":"additional","affiliation":[{"name":"Swedish Board of Agriculture , V\u00e5rsta Distriktsveterin\u00e4rstation,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Johnsson","sequence":"additional","affiliation":[{"name":"Morarp ,","place":["Sweden (Johnsson)"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Matiasek","sequence":"additional","affiliation":[{"name":"General Pathology and Neuropathology, Institute of Veterinary Pathology, Ludwig-Maximilians University , Munich,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CN","family":"Hahn","sequence":"additional","affiliation":[{"name":"Neuromuscular Disease Laboratory, University of Edinburgh , Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Malm","sequence":"additional","affiliation":[{"name":"Swedish University of Agricultural Sciences Department of Animal Breeding and Genetics, , Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5","family":"Hedhammar","sequence":"additional","affiliation":[{"name":"Swedish University of Agricultural Sciences Department of Clinical Sciences, , Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,11,1]]},"reference":[{"key":"2026020303382920000_b1","first-page":"8","article-title":"Comparative cerebellar disease in domestic animals","volume":"2","author":"de Lahunta","year":"1980","journal-title":"Compend Contin Educ Pract Vet"},{"key":"2026020303382920000_b2","first-page":"281","volume-title":"Veterinary Neuropathology","author":"Summers","year":"1995"},{"key":"2026020303382920000_b3","first-page":"437","volume-title":"Veterinary Neuropathology","author":"Summers","year":"1995"},{"key":"2026020303382920000_b4","volume-title":"Braund's Clinical Neurology in Small Animals: Localization, Diagnosis and Treatment","author":"Braund","year":"2003"},{"key":"2026020303382920000_b5","volume-title":"Braund's Clinical Neurology in Small Animals: Localization, Diagnosis and Treatment","author":"Braund","year":"2003"},{"key":"2026020303382920000_b6","first-page":"10","volume-title":"Handbook of Veterinary Neurology","author":"Lorenz","year":"2004","edition":"4th ed"},{"key":"2026020303382920000_b7","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1212\/WNL.25.8.781","article-title":"Frequency of nerve fiber degeneration of peripheral motor and sensory neurons in amyotrophic lateral sclerosis. 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