{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:00:58Z","timestamp":1791086458440,"version":"4.1.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2009,11,5]],"date-time":"2009-11-05T00:00:00Z","timestamp":1257379200000},"content-version":"vor","delay-in-days":2135,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2004,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The central bearded dragon (Pogona vitticeps) is a medium-sized lizard that is common in semiarid habitats in Australia and that potentially is at risk of fenitrothion exposure from use of the chemical in plague locust control. We examined the effects of single sublethal doses of this organophosphate (OP; low dose = 2.0 mg\/kg; high dose = 20 mg\/kg; control = vehicle alone) on lizard thermal preference, standard metabolic rate, and prey-capture ability. We also measured activities of plasma total cholinesterase (ChE) and acetylcholinesterase before and at 0, 2, 8, 24, 120, and 504 h after OP dosing. Predose plasma total ChE activity differed significantly between sexes and averaged 0.66 \u00b1 0.06 and 0.45 \u00b1 0.06 \u03bcmol\/min\/ml for males and females, respectively. Approximately 75% of total ChE activity was attributable to butyrylcholinesterase. Peak ChE inhibition reached 19% 2 h after OP ingestion in the low-dose group, and 68% 8 h after ingestion in high-dose animals. Neither OP doses significantly affected diurnal body temperature, standard metabolic rate, or feeding rate. Plasma total ChE levels remained substantially depressed up to 21 d after dosing in the high-dose group, making this species a useful long-term biomonitor of OP exposure in its habitat.<\/jats:p>","DOI":"10.1897\/02-555","type":"journal-article","created":{"date-parts":[[2005,3,19]],"date-time":"2005-03-19T11:08:50Z","timestamp":1111230530000},"page":"109-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey-capture ability in the Australian central bearded dragon (<i>Pogona vitticeps<\/i>, agamidae)"],"prefix":"10.1093","volume":"23","author":[{"given":"David","family":"Bain","sequence":"first","affiliation":[{"name":"Institute for Conservation Biology, University of Wollongong, Wollongong, New South Wales 2522, Australia"},{"name":"Department of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Buttemer","sequence":"additional","affiliation":[{"name":"Institute for Conservation Biology, University of Wollongong, Wollongong, New South Wales 2522, Australia"},{"name":"Department of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Astheimer","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia"},{"name":"Institute for Conservation Biology, University of Wollongong, Wollongong, New South Wales 2522, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Fildes","sequence":"additional","affiliation":[{"name":"Institute for Conservation Biology, University of Wollongong, Wollongong, New South Wales 2522, Australia"},{"name":"Department of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Hooper","sequence":"additional","affiliation":[{"name":"The Institute of Environmental and Human Health, Texas Tech University, Lubbock, Texas 79409, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2004,1,1]]},"reference":[{"key":"2025010612225825100_bib1","volume-title":"Australian Plague Locust Commission annual report, 95\/96","author":"Department of Primary Industry and Energy.","year":"1997"},{"key":"2025010612225825100_bib2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1071\/WR99060","article-title":"Review of the effects of organophosphorus and carbamate insecticides on vertebrates. Are there implications for locust management in Australia?","volume":"28","author":"Story","year":"2001","journal-title":"Wildl Res"},{"key":"2025010612225825100_bib3","volume-title":"Australian Reptiles and Frogs","author":"Hoser","year":"1989"},{"key":"2025010612225825100_bib4","volume-title":"A Photographic Guide to Snakes and other Reptiles of Australia","author":"Swan","year":"1995"},{"key":"2025010612225825100_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-08-091726-9.50005-7","volume-title":"Organophosphates: Chemistry, Fate, and Effects","author":"Chambers","year":"1992"},{"key":"2025010612225825100_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0301-0082(87)90008-6","article-title":"Mechanisms underlying sensitivity to organophosphorus anticholinesterase compounds","volume":"28","author":"Russell","year":"1987","journal-title":"Prog Neurobiol (NY)"},{"key":"2025010612225825100_bib7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/etc.5620120215","article-title":"Relationships between behaviour and the inhibition of acetylcholinesterase in birds exposed to organophosphorus pesticides","volume":"12","author":"Hart","year":"1993","journal-title":"Environ Toxicol Chem"},{"key":"2025010612225825100_bib8","volume-title":"Cholinesterase-inhibiting Insecticides","author":"Grue","year":"1991"},{"key":"2025010612225825100_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/icb\/37.4.369","article-title":"Neurophysiological and behavioural changes in non-target wildlife exposed to organophosphorus and carbamate pesticides: Thermoregulation, food consumption and reproduction","volume":"37","author":"Grue","year":"1997","journal-title":"Am Zool"},{"key":"2025010612225825100_bib10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/978-3-642-87810-7_25","volume-title":"Perspectives of Biophysical Ecology","author":"Dawson","year":"1975"},{"key":"2025010612225825100_bib11","volume-title":"Comparative Animal Physiology","author":"Withers","year":"1992"},{"key":"2025010612225825100_bib12","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/BF00212436","article-title":"Interspecies variation of \u201cB\u201d esterases in birds: The influence of size and feeding habits","volume":"31","author":"Fossi","year":"1996","journal-title":"Arch Environ Contam Toxicol"},{"key":"2025010612225825100_bib13","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","article-title":"A new and rapid colorimetric determination of acetylcholinesterase activity","volume":"7","author":"Ellman","year":"1961","journal-title":"Biochem Pharmacol"},{"key":"2025010612225825100_bib14","volume-title":"Cholinesterase-inhibiting Insecticides","author":"Fairbrother","year":"1991"},{"key":"2025010612225825100_bib15","volume-title":"Cholinesterase-inhibiting Insecticides","author":"Thompson","year":"1991"},{"key":"2025010612225825100_bib16","volume-title":"Encyclopedia of Toxicology","author":"Wexler","year":"1998"},{"key":"2025010612225825100_bib17","volume-title":"Biostatistical Analysis","author":"Zar","year":"1999","edition":"3rd ed."},{"key":"2025010612225825100_bib18","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1006\/jare.1996.0081","article-title":"Effects of body mass and temperature on standard metabolic rate of the herbivorous desert lizard Uromastyx philbyi","volume":"33","author":"Zari","year":"1996","journal-title":"J Arid Environ"},{"key":"2025010612225825100_bib19","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1152\/jappl.1972.33.2.261","article-title":"Determination of oxygen consumption by use of the paramagnetic oxygen analyzer","volume":"33","author":"Hill","year":"1972","journal-title":"J Appl Physiol"},{"key":"2025010612225825100_bib20","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1897\/1551-5028(1997)016<1954:SBEAAN>2.3.CO;2","article-title":"Serum B esterases as a nondestructive biomarker in the lizard Gallotia galloti experimentally treated with parathion","volume":"16","author":"Sanchez","year":"1997","journal-title":"Environ Toxicol Chem"},{"key":"2025010612225825100_bib21","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0269-7491(94)P4160-P","article-title":"The lizard Gallotia galloti as a bioindicator of organophosphorus contamination in the Canary Islands","volume":"87","author":"Fossi","year":"1995","journal-title":"Environ Pollut"},{"key":"2025010612225825100_bib22","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0143-1471(82)90044-7","article-title":"Responses of the iguanid lizard Anolis carolinensis to four organophosphorus pesticides","volume":"28","author":"Hall","year":"1982","journal-title":"Environ Pollut Ser A Ecol Biol"},{"key":"2025010612225825100_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/pest.1999.2471","article-title":"In vitro and in vivo cholinesterase inhibition in lacertids by phosphonate- and phosphorothioate-type organophosphates","volume":"67","author":"Sanchez-Hernandez","year":"2000","journal-title":"Pestic Biochem Physiol"},{"key":"2025010612225825100_bib24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1006\/eesa.1997.1560","article-title":"Serum B esterases as a nondestructive biomarker for monitoring the exposure of reptiles to organophosphorus insecticides","volume":"37","author":"Sanchez","year":"1997","journal-title":"Ecotoxicol Environ Saf"},{"key":"2025010612225825100_bib25","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1139\/y84-129","article-title":"Methyl parathion and fenvalerate toxicity in American kestrels: Acute physiological responses and effects of cold","volume":"62","author":"Rattner","year":"1984","journal-title":"Can J Physiol Pharmacol"},{"key":"2025010612225825100_bib26","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.nutr.19.1.247","article-title":"Energetics of free-ranging mammals, birds, and reptiles","volume":"19","author":"Nagy","year":"1999","journal-title":"Annu Rev Nutr"},{"key":"2025010612225825100_bib27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/B978-0-08-091726-9.50009-4","volume-title":"Organophosphates:Chemistry, Fates, and Effects","author":"Wilson","year":"1992"},{"key":"2025010612225825100_bib28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1086\/physzool.66.1.30158291","article-title":"Metabolism of a desert lizard: The effects of mass, sex, population of origin, temperature, time of day, and feeding on oxygen consumption of Sceloporus merriami","volume":"66","author":"Beaupre","year":"1993","journal-title":"Physiol Zool"},{"key":"2025010612225825100_bib29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2307\/1939476","article-title":"Interhabitat differences in energy acquisition and expenditure in a lizard","volume":"65","author":"Karasov","year":"1984","journal-title":"Ecology"},{"key":"2025010612225825100_bib30","first-page":"127","volume-title":"Biology of the Reptilia","author":"Bennett","year":"1976"},{"key":"2025010612225825100_bib31","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s004420050470","article-title":"Thermal ecology of the Australian agamid Pogona barbata","volume":"114","author":"Schauble","year":"1998","journal-title":"Oecologia"},{"key":"2025010612225825100_bib32","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1086\/physzool.36.3.30152307","article-title":"Control of changes in body temperature, metabolism, and circulation by the agamid lizard Amphibolurus barbatus","volume":"36","author":"Bartholomew","year":"1963","journal-title":"Physiol Zool"},{"key":"2025010612225825100_bib33","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0892-0362(94)90122-8","article-title":"Thermoregulation in laboratory mammals and humans exposed to anticholinesterase agents","volume":"16","author":"Gordon","year":"1994","journal-title":"Neurotoxicol Teratol"},{"key":"2025010612225825100_bib34","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0041-008X(76)90079-X","article-title":"Thermoregulation in mice treated with parathion, carbaryl, or DDT","volume":"35","author":"Ahdaya","year":"1976","journal-title":"Toxicol Appl Pharmacol"},{"key":"2025010612225825100_bib35","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1600-0773.1981.tb00896.x","article-title":"Influence of intoxication by anticholin-esterase agents on core temperature in rats: Relationships between hypothermia and acetylcholinesterase inhibition in different brain areas","volume":"49","author":"Coudray-Lucas","year":"1981","journal-title":"Acta Pharmacol Toxicol"},{"key":"2025010612225825100_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0892-0362(94)90002-7","article-title":"Thermoregulatory effects of chlorpyrifos in the rat: Long-term changes in cholinergic and noradrenergic sensitivity","volume":"16","author":"Gordon","year":"1994","journal-title":"Neurotoxicol Teratol"},{"key":"2025010612225825100_bib37","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1126\/science.188.4184.166","article-title":"Fever and survival","volume":"188","author":"Kluger","year":"1975","journal-title":"Science"},{"key":"2025010612225825100_bib38","first-page":"200","article-title":"Assessing hazards of organophosphate pesticides to wildlife","volume":"48","author":"Grue","year":"1983","journal-title":"N Am Wildl Nat Resour Conf"},{"key":"2025010612225825100_bib39","volume-title":"Biology of Cholinergic Function","author":"Goldberg","year":"1976"},{"key":"2025010612225825100_bib40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/BF00196217","article-title":"Effects of exposure to an organophosphate on the seed-handling efficiency of the house sparrow","volume":"53","author":"Fryday","year":"1994","journal-title":"Bull Environ Contam Toxicol"},{"key":"2025010612225825100_bib41","first-page":"91","article-title":"Effects of fenitrothion on survival, behavior, and brain cholinesterase activity of white-throated sparrows","volume":"12","author":"Forsyth","year":"1993","journal-title":"Environ Toxicol Chem"},{"key":"2025010612225825100_bib42","first-page":"141","article-title":"Thermal dependence of striking and prey capture by gopher snakes","volume":"74","author":"Greenwald","year":"1976","journal-title":"Copeia"}],"container-title":["Environmental Toxicology and Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1897%2F02-555","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/23\/1\/109\/59671703\/5620230116.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/etc\/article-pdf\/23\/1\/109\/59671703\/5620230116.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T12:23:41Z","timestamp":1736166221000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/etc\/article\/23\/1\/109\/7775135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1,1]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,1,1]]},"published-print":{"date-parts":[[2004,1,1]]}},"URL":"https:\/\/doi.org\/10.1897\/02-555","relation":{},"ISSN":["0730-7268","1552-8618"],"issn-type":[{"value":"0730-7268","type":"print"},{"value":"1552-8618","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2004,1,1]]},"published":{"date-parts":[[2004,1,1]]},"assertion":[{"value":"2002-11-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-05-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-11-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}