{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T21:50:19Z","timestamp":1791150619413,"version":"4.1.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"},{"start":{"date-parts":[[2009,12,9]],"date-time":"2009-12-09T00:00:00Z","timestamp":1260316800000},"content-version":"vor","delay-in-days":1683,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["setac.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2005,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We examined the tolerance development to mercury (Hg) by a population of freshwater zooplankton (Daphnia magna) with different pre-exposure histories to Hg. The growth and reproductive performance of the F1 offspring as affected by the maternal (F0) and offspring (F1) exposures was quantified. The Fo daphnids exposed to 2.5 and 25 nM of Hg for 4 d and followed by 4 d of depuration had elevated levels of Hg and metallothionein-like proteins (MTLPs), as well as higher tolerance to Hg toxicity than the control daphnids. The higher Hg tolerance may be attributed to the higher proportion of Hg partitioned to the MTLPs. Moreover, significant enhancement of Hg tolerance also was found in the F1 offspring originating from the F0 mothers exposed to 25 nM of Hg, but there was no significant induction of MTLPs in these F1 offspring when compared to the offspring from the control mothers. The Hg tissue concentrations in the F1 neonates were approximately 25% of those in the F0 adults. However, there was similar Hg tolerance in the F2 offspring originating from both the control and Hg-exposed F0 mothers, indicating that the Hg tolerance in the daphnids disappeared two generations after Hg contamination. Further exposure of the F1 offspring to different Hg concentrations (1.5 and 15 nM for 28 d) indicated that maternal exposure history did not affect their growth and reproductive performance, which solely were influenced by the offspring exposure. Unexpectedly, the F1 offspring exposed to Hg had significantly higher final wet weights and reproductive rates than the control groups, suggesting the possibility of Hg hormesis. Furthermore, the maternal exposure had no effect on the Hg accumulation and the MTLP concentrations in the F1 offspring. Therefore, we concluded that the Hg tolerance might disappear quickly once the Hg contamination was removed and the maternal exposure history was not important in determining the physiological performance and Hg accumulation of the subsequent generations.<\/jats:p>","DOI":"10.1897\/04-190r.1","type":"journal-article","created":{"date-parts":[[2005,4,25]],"date-time":"2005-04-25T16:50:38Z","timestamp":1114447838000},"page":"1228-1234","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Influences of maternal exposure on the tolerance and physiological performance of <i>Daphnia magna<\/i> under mercury stress"],"prefix":"10.1093","volume":"24","author":[{"given":"Martin T.K.","family":"Tsui","sequence":"first","affiliation":[{"name":"Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Xiong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,5,1]]},"reference":[{"key":"2025010318062346400_bib1","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.4319\/lo.1992.37.6.1313","article-title":"Mercury and methylmercury in individual zooplankton\u2014implications for bioaccumulation","volume":"37","author":"Watras","year":"1992","journal-title":"Limnol Oceanogr"},{"key":"2025010318062346400_bib2","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.4319\/lo.2000.45.7.1525","article-title":"Accumulation of heavy metals in food web components across a gradient of lakes","volume":"45","author":"Chen","year":"2000","journal-title":"Limnol Oceanogr"},{"key":"2025010318062346400_bib3","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1897\/02-407","article-title":"Inheritance of mercury tolerance in the aquatic oligochaete Tubifex tubifex","volume":"22","author":"Vidal","year":"2003","journal-title":"Environ Toxicol Chem"},{"key":"2025010318062346400_bib4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0166-445X(90)90075-Z","article-title":"Cadmium resistance in Daphnia magna","volume":"16","author":"Bodar","year":"1990","journal-title":"Aquat Toxicol"},{"key":"2025010318062346400_bib5","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/0742-8413(92)90088-O","article-title":"Induction of cadmium tolerance in 2 clones of Daphnia magna Straus","volume":"101","author":"Stuhlbacher","year":"1992","journal-title":"Comp Biochem Physiol C"},{"key":"2025010318062346400_bib6","first-page":"2875","article-title":"Acclimation-induced changes in the toxicity of zinc and cadmium to rainbow trout","volume":"18","author":"Stubblefield","year":"1999","journal-title":"Environ Toxicol Chem"},{"key":"2025010318062346400_bib7","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1021\/es0155534","article-title":"Uptake and efflux of Cd and Zn by the green mussel Perna viridis after metal pre-exposure","volume":"36","author":"Blackmore","year":"2002","journal-title":"Environ Sci Technol"},{"key":"2025010318062346400_bib8","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1021\/es034801o","article-title":"Understanding the differences in Cd and Zn bioaccumulation and subcellular storage among different populations of marine clams","volume":"38","author":"Shi","year":"2004","journal-title":"Environ Sci Technol"},{"key":"2025010318062346400_bib9","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0141-1136(97)00131-1","article-title":"Influence of chronic exposure to silver and mercury in the field on the bioaccumulation potential of the bivalve Macoma balthica","volume":"45","author":"Boisson","year":"1998","journal-title":"Mar Environ Res"},{"key":"2025010318062346400_bib10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0166-445X(92)90026-J","article-title":"Metallothioneins in metal regulation and toxicity in aquatic animals","volume":"22","author":"Roesijadi","year":"1992","journal-title":"Aquat Toxicol"},{"key":"2025010318062346400_bib11","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3354\/meps249183","article-title":"Subcellular compartmentalization of Cd and Zn in two bivalves. 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