{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:40:57Z","timestamp":1787802057855,"version":"build-2784847793"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T00:00:00Z","timestamp":1361836800000},"content-version":"vor","delay-in-days":4684,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Exper Analysis Behavior"],"published-print":{"date-parts":[[2000,5]]},"abstract":"<jats:p>\n                    This paper describes an olfactory discrimination procedure for mice that is inexpensively implemented and leads to rapid discrimination learning. Mice were first trained to dig in small containers of sand to retrieve bits of buried chocolate. For discrimination training, two containers were presented simultaneously for eight trials per session. One container held sand mixed with cinnamon, and the other held sand mixed with nutmeg. Both containers were baited with chocolate buried in the sand. One odor was designated S+, and mice were allowed to dig and retrieve the chocolate from this container. The other odor was S\u2010, and both containers were removed immediately if subjects began to dig in an S\u2010 container. After meeting a two\u2010session acquisition criterion, subjects were given a series of discrimination reversals. In Experiment 1, 12 Swiss\u2010Webster mice (6 male and 6 female) acquired the olfactory discrimination in three to five sessions and completed 3 to 10 successive discrimination reversals within a 50\u2010session testing limit. In Experiment 2, subjects were 14 Pah\n                    <jats:sup>enu2<\/jats:sup>\n                    mice, the mouse mutant for phenylketonuria; 7 were homozygotes in which the disorder was expressed (PKU), and 7 were heterozygotes with normal metabolism (non\u2010PKU). Thirteen mice completed pretraining in four to seven sessions, acquisition required 3 to 12 sessions, and all mice completed at least three reversals. Learning rates were similar in PKU and non\u2010PKU mice. We discuss issues related to implementation and several potentially useful procedural variations.\n                  <\/jats:p>","DOI":"10.1901\/jeab.2000.73-305","type":"journal-article","created":{"date-parts":[[2006,3,2]],"date-time":"2006-03-02T11:42:55Z","timestamp":1141299775000},"page":"305-318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["AN OLFACTORY DISCRIMINATION PROCEDURE FOR MICE"],"prefix":"10.1002","volume":"73","author":[{"given":"Sheila M.","family":"Mihalick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C.","family":"Langlois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"Krienke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William V.","family":"Dube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.112.6.1318"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/h0022328"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/379255a0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5420.1670"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/hbeh.1997.1382"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03395911"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198802000-00036"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.13.7109"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199607000-00005"},{"key":"e_1_2_1_11_1","first-page":"503","article-title":"Alprazolam dependence in mice","volume":"7","author":"Gallaher E. 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