{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T22:00:17Z","timestamp":1784757617735,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> An amnion\u2013chorion membrane is a placenta\u2010derived tissue that has been introduced recently as a guided tissue regeneration membrane in dentistry. Numerous growth factors, proteins, and stem cell reserves in amnion could help in accelerated wound healing and regeneration, whereas chorion is a rich source of various collagen and non\u2010collagen proteins. The present six\u2010patient observational case series compares amnion and chorion allografts for recession coverage.<\/jats:p><jats:p><jats:bold>Case Series:<\/jats:bold> Six healthy adult patients presenting with 12 Miller Class I recession defects were treated surgically with a modified coronally advanced flap along with amniotic membrane (group A) or chorion (group B) for coverage of the recession defects following a split\u2010mouth design. Clinical parameters measured at baseline, 3 months, and 6 months were width of keratinized gingiva (WKG), probing depth, recession height, clinical attachment level (CAL), and assessment of gingival biotype. Statistical analysis was done using paired and unpaired Student <jats:italic>t<\/jats:italic> test. The results showed statistically significant (<jats:italic>P<\/jats:italic> &lt;0.01) improvements in all clinical parameters at the 3\u2010 and 6\u2010month follow\u2010ups in both groups. Nine of 12 treated recession defects showed 100% root coverage. The gingival biotype also showed a thick biotype in 10 sites that had an initial thin biotype.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Both amnion and chorion membranes provided promising results in terms of root coverage, increased WKG, CAL gain, and thickness of the gingival biotype and can be used for periodontal plastic surgeries.<\/jats:p>","DOI":"10.1902\/cap.2015.150060","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T06:46:17Z","timestamp":1447310777000},"page":"118-126","source":"Crossref","is-referenced-by-count":12,"title":["Comparative Evaluation of the Efficacy of Human Chorion and Amnion With Coronally Advanced Flap for Recession Coverage: A Case Series"],"prefix":"10.1002","volume":"6","author":[{"given":"Aena Jain","family":"Pundir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vandita","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddharth","family":"Pundir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Diwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonika","family":"Bodhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.12.1840"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_9_4_1","first-page":"378","article-title":"Gingival augmentation with an acellular dermal matrix: Human histologic evaluation of a case \u2014Placement of the graft on periosteum","volume":"24","author":"Harris RJ","year":"2004","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_9_5_1","first-page":"65","article-title":"A novel dehydrated amnion allograft for use in the treatment of gingival recession: An observational case series","volume":"1","author":"Gurinsky B","year":"2009","journal-title":"J Implant Adv Clin Dent"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01456.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.6.316"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.7.779"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2007-0594"},{"key":"e_1_2_9_10_1","first-page":"1","article-title":"Amniotic membrane: A novel material for regeneration and repair","volume":"18","author":"Chopra A","year":"2013","journal-title":"J Biomim Biomater Tissue Eng"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2005.02285.x"},{"key":"e_1_2_9_12_1","first-page":"29","article-title":"Amniotic membrane in surgery","volume":"53","author":"Ganatra MA","year":"2003","journal-title":"J Pak Med Assoc"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v015a07"},{"key":"e_1_2_9_14_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_9_15_1","first-page":"57","article-title":"Placental tissues: Fixing smiles","volume":"7","author":"Gupta I","year":"2014","journal-title":"Int J Innov Sci Res"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200005000-00018"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/cap.2012.120039"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/cap.2015.150060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:39:17Z","timestamp":1760042357000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/cap.2015.150060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1902\/cap.2015.150060"],"URL":"https:\/\/doi.org\/10.1902\/cap.2015.150060","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"value":"2573-8046","type":"print"},{"value":"2163-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}