{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:45:21Z","timestamp":1781585121542,"version":"3.54.5"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1988,6]]},"abstract":"<jats:p>T<jats:sc>he effectiveness of diflunisal<\/jats:sc> as a preoperative medication to reduce pain following periodontal surgery was evaluated. Fifty patients were divided into two groups in a doubleblind random manner: Group one received preoperative difunisal and Group two received preoperative placebo. The preoperative diflunisal group reported significantly less discomfort (<jats:italic>P<\/jats:italic> &lt; 0.05) than the preoperative placebo group and used rescue medication significantly less often (<jats:italic>P<\/jats:italic> &lt; 0.01). Therapeutic doses of diflunisal, given presurgically, are significantly more effective than placebo in limiting postoperative pain associated with periodontal surgery.<\/jats:p>","DOI":"10.1902\/jop.1988.59.6.390","type":"journal-article","created":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T09:03:53Z","timestamp":1332320633000},"page":"390-393","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of Preoperative Diflunisal for Postoperative Pain Following Periodontal Surgery"],"prefix":"10.1002","volume":"59","author":[{"given":"James S.","family":"Minutello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald H.","family":"Newell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Thrash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geza T.","family":"Terezhalmy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1988,6]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1988.59.6.390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:20:08Z","timestamp":1760883608000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1988.59.6.390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["10.1902\/jop.1988.59.6.390"],"URL":"https:\/\/doi.org\/10.1902\/jop.1988.59.6.390","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,6]]}}}