{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T20:44:02Z","timestamp":1763585042002,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[1990,7,1]],"date-time":"1990-07-01T00:00:00Z","timestamp":646790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:p>I<jats:sc>nterproximal bony defects were treated<\/jats:sc> with either porous hydroxyapatite (PHA) or decalcified freeze\u2010dried bone allograft (DFDB) implants at two different clinical centers. Twelve paired defects in 12 patients were treated at each center. Six months postsurgically the defects were measured to assess changes from the presurgical status. No statistically significant differences were found between the groups in changes in gingival fluid, bleeding index, plaque index, or tooth mobility. The porous hydroxyapatite implant produced greater reduction in pocket depth (<jats:italic>P<\/jats:italic> = 0.03) and more gain in clinical attachment level (<jats:italic>P<\/jats:italic> = 0.001) and defect fill (<jats:italic>P<\/jats:italic> = 0.001) when compared with DFDB grafted sites. This study indicates that more clinical resolution of interproximal periodontal defects in humans can be obtained with the use of PHA than with the use of DFDB. <jats:italic>J Periodontol 1990<\/jats:italic>;<jats:italic>61<\/jats:italic>:<jats:italic>399<\/jats:italic>\u2013<jats:italic>404<\/jats:italic>.<\/jats:p>","DOI":"10.1902\/jop.1990.61.7.399","type":"journal-article","created":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T07:15:42Z","timestamp":1332314142000},"page":"399-404","source":"Crossref","is-referenced-by-count":35,"title":["Comparative Clinical Study of Porous Hydroxyapatite and Decalcified Freeze\u2010Dried Bone in Human Periodontal Defects"],"prefix":"10.1002","volume":"61","author":[{"given":"Silvia","family":"Oreamuno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vojislav","family":"Lekovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Barrie","family":"Kenney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Fermin A.","family":"Carranza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry H.","family":"Takei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Prokic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1990,7]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1990.61.7.399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:50:57Z","timestamp":1760867457000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1990.61.7.399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1902\/jop.1990.61.7.399"],"URL":"https:\/\/doi.org\/10.1902\/jop.1990.61.7.399","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}