{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T01:57:48Z","timestamp":1783216668478,"version":"3.54.6"},"reference-count":0,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[1990,8,1]],"date-time":"1990-08-01T00:00:00Z","timestamp":649468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1990,8]]},"abstract":"<jats:p>A <jats:sc>total of 57 bacterial strains<\/jats:sc> (26 different species) which may be isolated from subgingival plaque were tested for their in vitro susceptibility to phenoxyethanol, a commonly\u2010used antiseptic and preservative. Ninety\u2010five percent of the strains, including those associated with chronic inflammatory periodontal disease, were susceptible to concentrations of phenoxyethanol used topically (2% w\/v). Phenoxyethanol at a concentration of 1% (w\/v) was also found to have a rapid bactericidal effect achieving a 99.9% kill in 5 minutes or less for species such as <jats:italic>Bacteroides gingivalis<\/jats:italic>, <jats:italic>Fusobacterium nucleatum<\/jats:italic>, <jats:italic>Eikenella corrodens<\/jats:italic>, and <jats:italic>Wolinella recta<\/jats:italic>. Addition of Chlorhexidine to phenoxyethanol resulted in a mixture with increased antibacterial activity. For most bacterial strains, the presence of Chlorhexidine resulted in at least a four\u2010fold decrease in the concentration of phenoxyethanol required for inhibition of growth. These results imply that phenoxyethanol may be useful in the treatment of chronic inflammatory periodontal disease either by itself or in combination with Chlorhexidine. <jats:italic>J Periodontol 1990<\/jats:italic>; <jats:italic>61<\/jats:italic>:<jats:italic>536<\/jats:italic>\u2013 <jats:italic>541<\/jats:italic>.<\/jats:p>","DOI":"10.1902\/jop.1990.61.8.536","type":"journal-article","created":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T07:27:31Z","timestamp":1332314851000},"page":"536-541","source":"Crossref","is-referenced-by-count":10,"title":["Susceptibility of Oral Bacteria to Phenoxyethanol and Phenoxyethanol\/ Chlorhexidine Combinations"],"prefix":"10.1002","volume":"61","author":[{"given":"M.","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Stanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.N.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1990,8]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1990.61.8.536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T12:41:19Z","timestamp":1760877679000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1990.61.8.536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1990,8]]}},"alternative-id":["10.1902\/jop.1990.61.8.536"],"URL":"https:\/\/doi.org\/10.1902\/jop.1990.61.8.536","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,8]]}}}