{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:58:02Z","timestamp":1777539482343,"version":"3.51.4"},"reference-count":0,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[1991,10,1]],"date-time":"1991-10-01T00:00:00Z","timestamp":686275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1991,10]]},"abstract":"<jats:p>T<jats:sc>he purpose of this study was to determine<\/jats:sc> the incidence of bacteremia after a single professional subgingival irrigation with a 0.12% Chlorhexidine gluconate mouthrinse (CHX) as well as after a subsequent scaling and root planing (S\/RP) during the same visit. Thirty subjects each with at least 1 site that probed 4 mm or more and bled on probing were randomly assigned to the following groups: 1) irrigation with 0.12% CHX; 2) irrigation with sterile water; and 3) non\u2010irrigated controls. To begin the study blood was drawn just before and 2 minutes after irrigation. Thirty minutes later, blood was drawn again just before and 2 minutes after S\/RP at the same site. Specimens were cultured for anaerobic and aerobic microorganisms using standard cultural techniques. Eighteen blood cultures from 15 subjects yielded positive cultures resulting in 23 isolates. Gram\u2010positive rods comprised 34.8% of the total isolates; Gram\u2010positive cocci 34.8%, Gram\u2010negative rods 21.7%, and Gram\u2010negative cocci 8.7%. In the CHX group, bacteremia was detected in 5 subjects after irrigation and in 2 other subjects after S\/RP. In the water group, bacteremia was detected in one subject after irrigation and in 4 subjects after S\/RP. The control group had 3 bacteremias after S\/RP. There was no significant difference between the incidence of bacteremia associated with irrigation by CHX or sterile water (<jats:italic>P<\/jats:italic> = 0.141). There was also no significant difference in the incidence of bacteremia after S\/RP between the CHX and sterile water irrigation groups and in patients who did not receive irrigation (control group) (<jats:italic>P<\/jats:italic> = 0.88). Thus it appears that subgingival irrigation, with or without medication, has no effect on the incidence of bacteremia following a subsequent S\/RP. <jats:italic>J Periodontol 1991; 62:602\u2013607.<\/jats:italic><\/jats:p>","DOI":"10.1902\/jop.1991.62.10.602","type":"journal-article","created":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T03:52:00Z","timestamp":1332301920000},"page":"602-607","source":"Crossref","is-referenced-by-count":68,"title":["Bacteremia Following Subgingival Irrigation and Scaling and Root Planing"],"prefix":"10.1002","volume":"62","author":[{"given":"John E.","family":"Lofthus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc Y.","family":"Waki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Jolkovsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"Otomo\u2010Corgel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Flemmig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushma","family":"Nachnani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,10]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1991.62.10.602","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1991.62.10.602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T12:39:59Z","timestamp":1760877599000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1991.62.10.602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,10]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1991,10]]}},"alternative-id":["10.1902\/jop.1991.62.10.602"],"URL":"https:\/\/doi.org\/10.1902\/jop.1991.62.10.602","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,10]]}}}