{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:34:32Z","timestamp":1761975272803,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[1991,10,1]],"date-time":"1991-10-01T00:00:00Z","timestamp":686275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1991,10]]},"abstract":"<jats:p>A<jats:sc>ngioedema is a diffuse swelling<\/jats:sc> of the subcutaneous or submucosal tissues that occurs in both hereditary and non\u2010hereditary forms. It can be a temporarily disfiguring condition, but not usually a serious one unless the airway is compromised. In the majority of cases, no underlying cause can be identified. In this report, a case of \u201cidiopafhic\u201d angioedema that occurred while performing a periodontal surgical procedure is presented. This case is interesting because the patient was on long\u2010term use of an angiotensinconverting enzyme [ACE] inhibitor for hypertension, and recent evidence has shown that ACE inhibitors suppress the breakdown of circulating bradykinins. With high plasma levels of bradykinins, a local anesthetic, periodontal surgical procedures, or even emotional stress may trigger an attack of angioedema. Practitioners should be aware of the pharmacologic side effects of ACE inhibitors and be prepared to handle an emergency if a patient's airway becomes compromised. <jats:italic>J Periodontol 1991;62:643\u2013645.<\/jats:italic><\/jats:p>","DOI":"10.1902\/jop.1991.62.10.643","type":"journal-article","created":{"date-parts":[[2012,3,21]],"date-time":"2012-03-21T03:52:00Z","timestamp":1332301920000},"page":"643-645","source":"Crossref","is-referenced-by-count":10,"title":["Angioedema as a Complication in Periodontal Surgery: Report of a Case"],"prefix":"10.1002","volume":"62","author":[{"given":"Mark E.","family":"Peacock","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott L.","family":"Strong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert F.","family":"Prior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert B.","family":"O'Neal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas E.","family":"Van Dyke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,10]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1991.62.10.643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T12:39:58Z","timestamp":1760877598000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1991.62.10.643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,10]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1991,10]]}},"alternative-id":["10.1902\/jop.1991.62.10.643"],"URL":"https:\/\/doi.org\/10.1902\/jop.1991.62.10.643","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[1991,10]]}}}