{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T23:12:43Z","timestamp":1780960363389,"version":"3.54.1"},"reference-count":0,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[1996,10,1]],"date-time":"1996-10-01T00:00:00Z","timestamp":844128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1996,10]]},"abstract":"<jats:p>W<jats:sc>eary\u2010kindler syndrome is a rare and poorly<\/jats:sc> understood genetic disorder that has manifestations of both epidermolysis bullosa and poikiloderma congenitale. There are approximately 70 cases documented in the past 40 years but no cases appear in the dental literature, although dental findings have been discussed superficially in dermatological and pediatrie publications. This case reports on the periodontal findings and treatment for a 16\u2010year\u2010old female diagnosed with the syndrome. Early exfoliation of deciduous teeth, severe periodontal bone loss around many permanent teeth, and fragile bleeding gingiva were key features. Microbiological testing revealed an absence of <jats:italic>Actinobacillus actinomycetemcomitans<\/jats:italic> and low levels of other commonly accepted periodontal pathogens. Tests for inflammation, including AST and elastase, were positive prior to therapy and greatly decreased after mechanical root instrumentation. A beneficial effect of non\u2010surgical periodontal therapy was observed in the short\u2010term follow\u2010up. <jats:italic>J Periodontol 1996;67:1004\u20131010<\/jats:italic>.<\/jats:p>","DOI":"10.1902\/jop.1996.67.10.1004","type":"journal-article","created":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T19:30:31Z","timestamp":1332271831000},"page":"1004-1010","source":"Crossref","is-referenced-by-count":34,"title":["Early\u2010Onset Periodontitis Associated With Weary\u2010Kindler Syndrome: A Case Report"],"prefix":"10.1002","volume":"67","author":[{"given":"Colin B.","family":"Wiebe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Silver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu S.","family":"Larjava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,10]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1996.67.10.1004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:41:22Z","timestamp":1760881282000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1996.67.10.1004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,10]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1996,10]]}},"alternative-id":["10.1902\/jop.1996.67.10.1004"],"URL":"https:\/\/doi.org\/10.1902\/jop.1996.67.10.1004","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,10]]}}}