{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T02:09:02Z","timestamp":1769047742484,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[1999,4,1]],"date-time":"1999-04-01T00:00:00Z","timestamp":922924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[1999,4]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold>The aims of this study were to investigate the extent and distribution of bone loss in subjects with early\u2010onset periodontitis (EOP) referred for periodontal care and to study the relationship between smoking and EOP.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A total of 71 consecutive referrals (21 male, 50 female) under 35 years old, who were otherwise healthy, with a clinical diagnosis of severe periodontitis were recruited for the study. Bone loss was measured from available radiographs using a Schei ruler to identify 2 patterns of destruction: localized (LEOP) in 41 (58%) and generalized early\u2010onset periodontitis (GEOP) in 30 (42%) subjects.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The study population had a mean of 25.0 (SD 2.4) teeth, excluding third molars, and mean bone loss of 28.7% (SD 13.0). Bone loss was more severe in the maxilla, 30.9% (SD 13.8) compared with 26.6% (SD 14.0) in the lower arch. More than one\u2010third (36%) of the teeth examined had at least 30% bone loss. Mean smoking experience was 9.2 pack years (SD 5.6), and 39 (55%) of the EOP subjects smoked. Smokers had significantly more maxillary bone loss than non\u2010smokers. A much higher proportion of GEOP (70%) currently smoked compared with 44% of LEOP, <jats:italic>P<\/jats:italic> = 0.029.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> It is concluded that young adults with earlyonset forms of periodontitis often have advanced periodontal destruction before they are referred for specialist care. In addition, there was a relationship between smoking and severe bone destruction in subjects with EOP, particularly those with generalized disease. <jats:italic>J Periodontol 1999;70:394\u2010401.<\/jats:italic><\/jats:p>","DOI":"10.1902\/jop.1999.70.4.394","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T06:06:53Z","timestamp":1107324413000},"page":"394-401","source":"Crossref","is-referenced-by-count":22,"title":["Smoking and Patterns of Bone Loss in Early\u2010Onset Periodontitis"],"prefix":"10.1002","volume":"70","author":[{"given":"Brian H.","family":"Mullally","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanaid","family":"Breen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard J.","family":"Linden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1999,4]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.1999.70.4.394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:39:16Z","timestamp":1760881156000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.1999.70.4.394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,4]]}},"alternative-id":["10.1902\/jop.1999.70.4.394"],"URL":"https:\/\/doi.org\/10.1902\/jop.1999.70.4.394","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,4]]}}}