{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:16:57Z","timestamp":1760919417443,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:p><jats:italic><jats:bold>Background:<\/jats:bold> Erythema multiforme (EM) is a complex disease that may have cutaneous and\/or mucosal involvement. The severity may range from mild to severe and potentially life threatening. The literature cites many factors including viruses, infections, and medications as causes. This report documents a patient who developed EM secondary to a herpes simplex viral (HSV) infection.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Methods:<\/jats:bold> Two weeks following an eruption of herpes labialis, a 20\u2010year\u2010old white female patient developed acutely painful oral and labial ulcers accompanied by target skin lesions. A diagnosis of erythema multiforme (EM) was made. The patient was treated with antivirals, analgesics, and symptomatic therapy.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Results:<\/jats:bold> Nine days after the onset of symptoms, the oral and cutaneous lesions had started to heal and the patient no longer required pain medication.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Conclusions:<\/jats:bold> Although the etiology of EM is still often unknown, infections with herpes simplex virus have been implicated as a possible precipitating factor. This case illustrates the association of the occurrence of EM with an HSV infection.<\/jats:italic> J Periodontol 2001;72:953\u2010;957.<\/jats:p>","DOI":"10.1902\/jop.2001.72.7.953","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:00:05Z","timestamp":1107327605000},"page":"953-957","source":"Crossref","is-referenced-by-count":7,"title":["Erythema Multiforme Secondary to Herpes Simplex Infection: A Case Report"],"prefix":"10.1002","volume":"72","author":[{"given":"Lilibeth","family":"Ayangco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip J.","family":"Sheridan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy S.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,7]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2001.72.7.953","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:34:22Z","timestamp":1760862862000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2001.72.7.953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["10.1902\/jop.2001.72.7.953"],"URL":"https:\/\/doi.org\/10.1902\/jop.2001.72.7.953","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}