{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:29:56Z","timestamp":1760920196640,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p><jats:italic><jats:bold>Background:<\/jats:bold> Langerhans' cell histiocytosis (LCH) is a rare disorder in which a neoplastic proliferation of cells similar to the Langerhans' cell of the epidermis is observed. The disease may affect different organs as solitary or multiple lesions with a complete dissemination in different organs such as the bone (jaws), lung, hypothalamus, skin and mucous membranes, lymph nodes, liver, and other tissues. Although LCH is considered a childhood or juvenile disease, the diagnosis is often made in adults, and in many cases, a juvenile form progresses into adult life. Hand\u2010Schuller\u2010Christian disease (HSCD) is an LCH form in which the typical lesions involve the cranial bones, the eyes, and the pituitary gland.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Methods:<\/jats:bold> This article describes a case of a patient diagnosed, through periodontal lesions and diabetes insipidus, as having Langerhans' cell histiocytosis.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Conclusion:<\/jats:bold> As far as LCH lesions appearing in periodontal tissues, the periodontist should be involved in the detection of oral lesions.<\/jats:italic> J Periodontol 2002;73:1528\u20101533.<\/jats:p>","DOI":"10.1902\/jop.2002.73.12.1528","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:16:15Z","timestamp":1107328575000},"page":"1528-1533","source":"Crossref","is-referenced-by-count":13,"title":["Langerhans' Cell Histiocytosis Diagnosed Through Periodontal Lesions: A Case Report"],"prefix":"10.1002","volume":"73","author":[{"given":"Leonardo","family":"Muzzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovan Paolo Pini","family":"Prato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Ficarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,12]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2002.73.12.1528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:46:57Z","timestamp":1760870817000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2002.73.12.1528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1902\/jop.2002.73.12.1528"],"URL":"https:\/\/doi.org\/10.1902\/jop.2002.73.12.1528","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2002,12]]}}}