{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:03:24Z","timestamp":1790190204573,"version":"4.1.0"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2002,6,1]],"date-time":"2002-06-01T00:00:00Z","timestamp":1022889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2002,6]]},"abstract":"<jats:p><jats:italic><jats:bold>Background:<\/jats:bold> Cicatricial pemphigoid (benign mucous membrane pemphigoid) is an autoimmune vesiculobullous disease that affects mucosal tissues of adults and rarely presents in children. Only 9 cases in the English literature have reported cicatricial pemphigoid in children, primarily as oral mucosal lesions. This paper presents a case of childhood cicatricial pemphigoid that clinically manifested as necrotizing ulcerative gingivitis (NUG).<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Methods:<\/jats:bold> A 9\u2010year\u2010old girl presented with gingival bleeding and discomfort for 2 weeks. NUG was suspected and the patient was treated with antibiotics and an oral hygiene regimen. When the condition did not improve after repeated treatment trials, routine hematoxylin and eosin (H&amp;E) and direct immunofluorescence examinations were performed.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Results:<\/jats:bold> Microscopic examination of H&amp;E stained sections showed a non\u2010specific ulceration with chronic inflammation. Direct immunofluorescence studies of peri\u2010lesional tissue showed linear deposition of C3 at the basement membrane zone that was consistent with a diagnosis of cicatricial pemphigoid.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Conclusion:<\/jats:bold> Cicatricial pemphigoid is an autoimmune ulcerative condition that is rarely seen in children. Immunofluorescence studies are essential to differentiate this condition from other ulcerative oral lesions.<\/jats:italic> J Periodontol 2002;73:657\u2010663.<\/jats:p>","DOI":"10.1902\/jop.2002.73.6.657","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T06:15:30Z","timestamp":1107324930000},"page":"657-663","source":"Crossref","is-referenced-by-count":15,"title":["Oral Pemphigoid Masquerading as Necrotizing Ulcerative Gingivitis in a Child"],"prefix":"10.1002","volume":"73","author":[{"given":"Nour J.","family":"Musa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis","family":"Humphreys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Aguirre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirdza E.","family":"Neiders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,6]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2002.73.6.657","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:03:32Z","timestamp":1760868212000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2002.73.6.657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["10.1902\/jop.2002.73.6.657"],"URL":"https:\/\/doi.org\/10.1902\/jop.2002.73.6.657","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,6]]}}}