{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:25:20Z","timestamp":1760919920819,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2002,7,1]],"date-time":"2002-07-01T00:00:00Z","timestamp":1025481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p><jats:italic><jats:bold>Background:<\/jats:bold> Connective tissue disorders, such as some forms of Ehlers\u2010Danlos syndrome, have been associated with severe periodontitis.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Methods:<\/jats:bold> This report describes a case of Marfan's syndrome, an inherited disorder of connective tissue caused by mutations in the fibrillin\u20101 gene, in which the patient presented with severe periodontitis.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Results:<\/jats:bold> At examination, an average full\u2010mouth clinical attachment level loss of 5.6 \u00b1 2.1 mm, furcation involvement, and severe alveolar bone loss were observed in a 41\u2010year\u2010old Caucasian male. Tooth hypermobility was also present.<\/jats:italic><\/jats:p><jats:p><jats:italic><jats:bold>Conclusions:<\/jats:bold> This case appears to be the first documentation of severe periodontitis in a patient with Marfan's syndrome. It supports the hypothesis that a variety of connective tissue disorders may confer increased susceptibility to periodontal tissue breakdown.<\/jats:italic> J Periodontol 2002;73:823\u2010826.<\/jats:p>","DOI":"10.1902\/jop.2002.73.7.823","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:23:52Z","timestamp":1107329032000},"page":"823-826","source":"Crossref","is-referenced-by-count":34,"title":["Severe Periodontitis in Marfan's Syndrome: A Case Report"],"prefix":"10.1002","volume":"73","author":[{"given":"Antje M.","family":"Straub","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney","family":"Grahame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crispian","family":"Scully","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio S.","family":"Tonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,7]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2002.73.7.823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:52:32Z","timestamp":1760867552000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2002.73.7.823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,7]]}},"alternative-id":["10.1902\/jop.2002.73.7.823"],"URL":"https:\/\/doi.org\/10.1902\/jop.2002.73.7.823","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}