{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:10:59Z","timestamp":1767625859814,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2003,11,1]],"date-time":"2003-11-01T00:00:00Z","timestamp":1067644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The purpose of this study was to compare 12\u2010month clinical responses to mechanical periodontal treatment in Chinese chronic periodontitis patients at sites with and without <jats:italic>Actinobacillus actinomycetemcomitans<\/jats:italic> at baseline, and to investigate the ability of mechanical periodontal treatment to eliminate <jats:italic>A. actinomycetemcomitans<\/jats:italic>.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Nineteen patients and a total of 76 selected sites with a mean probing depth (PD) of \u22657 mm were studied. Whole mouth presence or absence of supragingival plaque (Pl%), bleeding on probing (BOP%), probing depth (PD), and probing attachment level (PAL) were recorded at six sites per tooth at baseline and after 3, 9, and 12 months. Baseline subgingival plaque samples were taken from the deepest PD site in each quadrant using sterile paper points and were cultured on TSBV plates for 5 days in a 5% CO<jats:sub>2<\/jats:sub>\u2010air incubator. All sites received mechanical periodontal treatment, which included oral hygiene instructions and supragingival and subgingival instrumentation with or without surgical access, with maintenance care being provided once every 3 months thereafter.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> At baseline, <jats:italic>A. actinomycetemcomitans<\/jats:italic> was isolated in 13 of the 19 subjects (68%) and in 29 out of the 76 sampled sites (38%). At the end of 12 months, in three of the initially <jats:italic>A. actinomycetemcomitans<\/jats:italic>positive subjects, <jats:italic>A. actinomycetemcomitans<\/jats:italic> was not detected in the sampled sites, while one subject, in whom <jats:italic>A. actinomycetemcomitans<\/jats:italic> was not initially found at the sampled sites was <jats:italic>A. actinomycetemcomitans<\/jats:italic>\u2010positive at 12 months. Multi\u2010level variance component models showed there was no statistically significant difference in all clinical parameters between <jats:italic>A. actinomycetemcomitans<\/jats:italic>\u2010positive and \u2010negative subjects (<jats:italic>P<\/jats:italic> &gt;0.05). In the sampled sites of the initially <jats:italic>A. actinomycetemcomitans<\/jats:italic>\u2010positive subjects, the mean PD was reduced from 7.6 \u00b1 1.6 mm to 3.2 \u00b1 1.8 mm, the mean PAL gain was 1.4 \u00b1 2.0 mm, and the mean recession was 3.0 \u00b1 2.3 mm. The corresponding figures in the sampled sites of the initially <jats:italic>A. actinomycetemcomitans<\/jats:italic>\u2010negative subjects were 7.5 \u00b1 1.6 mm to 2.7 \u00b1 1.0 mm, 2.3 \u00b1 2.6 mm and 2.4 \u00b1 2.2 mm for mean PD changes, PAL gain, and mean recession, respectively.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Favorable clinical responses to mechanical periodontal therapy may occur in Chinese chronic periodontitis patients at sites infected with <jats:italic>A. actinomycetemcomitans<\/jats:italic>. The mere detection of subgignival <jats:italic>A. actinomycetemcomitans<\/jats:italic> does not necessarily imply poorer treatment outcomes in the control of chronic periodontitis. <jats:italic>J Periodontol 2003;74:1582\u20101588<\/jats:italic>.<\/jats:p>","DOI":"10.1902\/jop.2003.74.11.1582","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:34:46Z","timestamp":1107329686000},"page":"1582-1588","source":"Crossref","is-referenced-by-count":7,"title":["Clinical Responses to Mechanical Periodontal Treatment in Chinese Chronic Periodontitis Patients with and without <i>Actinobacillus actinomycetemcomitans<\/i>"],"prefix":"10.1002","volume":"74","author":[{"given":"Kenny S.K.","family":"Tong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwan\u2010Yat","family":"Zee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae\u2010Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esmonde F.","family":"Corbet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,11]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2003.74.11.1582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T12:57:59Z","timestamp":1760878679000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2003.74.11.1582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2003,11]]}},"alternative-id":["10.1902\/jop.2003.74.11.1582"],"URL":"https:\/\/doi.org\/10.1902\/jop.2003.74.11.1582","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2003,11]]}}}