{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:37:47Z","timestamp":1780630667262,"version":"3.54.1"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2003,6,1]],"date-time":"2003-06-01T00:00:00Z","timestamp":1054425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2003,6]]},"abstract":"Background:<\/jats:bold> No information exists on periodontitis\u2010associated subgingival microbiota from Turkey. We determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a Turkish study population.<\/jats:p>Methods:<\/jats:bold> Subgingival microbial samples were obtained from patients with localized (LAgP, N = 18) or generalized (GAgP, N = 17) types of aggressive periodontitis, generalized chronic periodontitis (GCP, N = 14), and non\u2010periodontitis subjects (N = 20). Culture methods were used to recover 6 periodontal bacterial species and yeasts, and a polymerase chain reaction technique was used to detect Actinobacillus actinomycetemcomitans<\/jats:italic> and Porphyromonas gingivalis<\/jats:italic>. Intraspecies characterization of A. actinomycetemcomitans<\/jats:italic> was carried out by serotyping and genotyping.<\/jats:p>Results:<\/jats:bold> All species, except for Micromonas micros<\/jats:italic> (formerly Peptostreptococcus micros<\/jats:italic>) occurred more frequently (P<\/jats:italic> <0.05) in periodontitis than non\u2010periodontitis subjects. Detection frequencies for Tannerella forsythensis<\/jats:italic> (formerly Bacteroides forsythus<\/jats:italic>) and Campylobacter rectus<\/jats:italic> differed among the periodontitis subgroups; the lowest frequency occurred in LAgP. The mean proportions of A. actinomycetemcomitans<\/jats:italic>, P. gingivalis<\/jats:italic>, and C. rectus<\/jats:italic> were higher (P<\/jats:italic> <0.008) in GAgP than in non\u2010periodontitis subjects. Significant positive associations were seen between 7 of the 22 possible combinations (P<\/jats:italic> <0.05). A. actinomycetemcomitans<\/jats:italic> serotype c (34%) and non\u2010serotypeable isolates (34%) were the most common antigenic types among the 305 strains analyzed. Eleven arbitrarily primed (AP)\u2010PCR genotypes were distinguished among 273 isolates from 29 subjects. Yeasts were found in 23% of the 69 subjects.<\/jats:p>Conclusions:<\/jats:bold> The results on the Turkish study population were generally in line with earlier reports on the occurrence and interspecies relationships of certain bacteria in periodontitis. However, A. actinomycetemcomitans<\/jats:italic> was not overrepresented in LAgP, and the serotype distribution resembled that reported from the East. The high frequency of non\u2010serotypeable isolates suggests local characteristics of the species. J Periodontol 2003; 74:803\u2010814<\/jats:italic>.<\/jats:p>","DOI":"10.1902\/jop.2003.74.6.803","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:40:58Z","timestamp":1107330058000},"page":"803-814","source":"Crossref","is-referenced-by-count":41,"title":["Subgingival Microflora in Turkish Patients with Periodontitis"],"prefix":"10.1002","volume":"74","author":[{"given":"Ba\u015fak","family":"Dog\u0360an","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Antinheimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"\u00c7etiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fen","family":"Bodur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclnur","family":"Emingil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eralp","family":"Buduneli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Uygur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"Firatli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lakio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirkka","family":"Asikainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,6]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2003.74.6.803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:01:05Z","timestamp":1760882465000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2003.74.6.803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["10.1902\/jop.2003.74.6.803"],"URL":"https:\/\/doi.org\/10.1902\/jop.2003.74.6.803","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}