{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:05:48Z","timestamp":1761717948118,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T00:00:00Z","timestamp":1059696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2003,8]]},"abstract":"<jats:p><jats:italic><jats:bold>Background:<\/jats:bold> Zimmermann\u2010Laband syndrome is a rare autosomal dominant disorder that is characterized by gingival fibromatosis, ear, nose, bone, and nail defects, and hepatosplenomegaly<\/jats:italic>.<\/jats:p><jats:p><jats:italic><jats:bold>Methods:<\/jats:bold> This case report describes the clinical presentation and periodontal findings in a 13\u2010year old female patient with previously undiagnosed Zimmermann\u2010Laband syndrome<\/jats:italic>.<\/jats:p><jats:p><jats:italic><jats:bold>Results:<\/jats:bold> Clinical and radiographic findings and genetic counseling confirmed the diagnosis of Zimmermann\u2010Laband syndrome. The most striking oral findings were the presence of gingival enlargement involving both the maxillary and mandibular arches, anterior open bite, non\u2010erupted teeth, and two supernumerary teeth. Periodontal treatment consisted of gingivectomy in four quadrants. Histopathologic evaluation of excised tissue supported the diagnosis of gingival fibromatosis. The patient was referred for appropriate orthodontic treatment and genetic counseling, and has been closely followed for the earliest signs of hepatosplenomegaly<\/jats:italic>.<\/jats:p><jats:p><jats:italic><jats:bold>Conclusions:<\/jats:bold> Dental practitioners should be alert for developmental abnormalities that may occur in patients with gingival fibromatosis as this may indicate the presence of a rare disorder like Zimmermann\u2010 Laband syndrome. A comprehensive medical history and physical systemic evaluation are essential for correct diagnosis and treatment of these cases<\/jats:italic>. J Periodontol 2003;74:1225\u20101230.<\/jats:p>","DOI":"10.1902\/jop.2003.74.8.1225","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T07:44:44Z","timestamp":1107330284000},"page":"1225-1230","source":"Crossref","is-referenced-by-count":21,"title":["A Case of Zimmermann\u2010Laband Syndrome with Supernumerary Teeth"],"prefix":"10.1002","volume":"74","author":[{"given":"Marinella","family":"Holzhausen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda de Oliveira Bello","family":"Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds Carlos","family":"Spolidorio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valter Curi","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana Regina Perez","family":"Orrico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,8]]},"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2003.74.8.1225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T09:15:17Z","timestamp":1760865317000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2003.74.8.1225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["10.1902\/jop.2003.74.8.1225"],"URL":"https:\/\/doi.org\/10.1902\/jop.2003.74.8.1225","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}