{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:29:01Z","timestamp":1787023741316,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The aim of the present study was to evaluate the clinical effects of one\u2010stage periodontal debridement with an ultrasonic instrument, associated with 0.5% povidone (pvp)\u2010iodine irrigation in patients with chronic periodontitis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Forty\u2010five patients were randomly assigned into three groups: the control group (CG) received quadrant root planing at 1\u2010week intervals over four consecutive sessions; the periodontal debridement plus pvp\u2010iodine group (PD\u2010PIG) received a 45\u2010minute full\u2010mouth debridement with an ultrasonic instrument, associated with 0.5% pvp\u2010iodine irrigation; and the periodontal debridement group (PDG) received a 45\u2010minute full\u2010mouth periodontal debridement with an ultrasonic instrument, associated with NaCl irrigation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    At the 3\u2010month evaluation, the mean probing depth (PD) reduction in CG was 2.51 \u00b1 0.52 mm, 2.53 \u00b1 0.50 mm in PD\u2010PIG, and 2.58 \u00b1 0.60 mm in PDG (\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.05). The clinical attachment level (CAL) analysis showed a statistically significant gain in all groups compared to baseline (1.87 \u00b1 0.56 mm [CG], 1.94 \u00b1 0.70 mm [PD\u2010PIG], and 1.99 \u00b1 0.92 mm [PDG]). Intergroup analysis of PD and CAL at 1 and 3 months showed no differences (\n                    <jats:italic>P<\/jats:italic>\n                    &gt;0.05). The N\u2010benzoyl\u2010L\u2010arginine\u2010p\u2010nitroanilide (BAPNA) test showed a significant reduction in trypsin activity only during the first month (\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.05); at 3 months there were no differences compared to baseline (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.80).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    This study provides no evidence that pvp\u2010iodine is effective as an adjunct for one\u2010stage periodontal debridement.\n                  <\/jats:p>","DOI":"10.1902\/jop.2006.050154","type":"journal-article","created":{"date-parts":[[2006,3,2]],"date-time":"2006-03-02T15:32:59Z","timestamp":1141313579000},"page":"498-505","source":"Crossref","is-referenced-by-count":49,"title":["Periodontal Debridement With Povidone\u2010Iodine in Periodontal Treatment: Short\u2010Term Clinical and Biochemical Observations"],"prefix":"10.1002","volume":"77","author":[{"given":"Guilherme M.","family":"Zanatta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Bittencourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Francisco H.","family":"Nociti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enilson A.","family":"Sallum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio W.","family":"Sallum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio 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