{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:49:15Z","timestamp":1793760555626,"version":"4.6.1"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2006,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Correcting recession defects is one of the goals of periodontal therapy, and the efficacy and predictability of the various techniques are important considerations for both patients and clinicians. Several reports have examined the outcome of gingival recession treatment by means of coronally positioned flaps (CPF) and enamel matrix derivative (EMD). The purpose of this study was to clinically evaluate the use of EMD in association with CPF to cover localized gingival recessions compared to CPF alone.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Twenty\u2010two patients with Miller Class I or II gingival recessions &gt;2 mm were included. One recession from each patient was treated in the study. Two treatments were randomly assigned: coronally positioned flap with EMD (test) and coronally positioned flap alone (control). Clinical parameters measured at baseline and 1, 6, and 12 months included gingival index, plaque index, probing depth, clinical attachment level, vertical and horizontal recession, and width of keratinized gingiva.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> At 12 months, both treatment modalities showed significant root coverage, gain in clinical attachment, and gain in width of keratinized gingiva (<jats:italic>P<\/jats:italic> &lt;0.05). Vertical recessions were reduced from 2.68 \u00b1 1.63 mm to 0.36 \u00b1 0.60 mm in the test group and from 2.31 \u00b1 1.52 mm to 0.90 \u00b1 0.95 mm in the control group. Horizontal recessions decreased from 4.27 \u00b1 2.06 mm to 0.77 \u00b1 0.87 mm in the test group and from 3.68 \u00b1 1.91 mm to 1.72 \u00b1 1.31 mm in the control group. Changes in keratinized gingiva went from 3.81 \u00b1 1.95 mm to 4.63 \u00b1 2.15 mm in the test group and from 3.31 \u00b1 1.81 mm to 3.27 \u00b1 1.80 mm in the control group. When both treatments were compared at 12 months, there was a significant difference in vertical tooth coverage and gain in keratinized gingiva in favor of the experimental group (<jats:italic>P<\/jats:italic> &lt;0.05). The average percentage of root coverage for test and control groups was 88.6% and 62.2%, respectively.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The coronally positioned flap alone or with EMD is an effective procedure to cover localized gingival recessions. The addition of EMD significantly improves the amount of root coverage.<\/jats:p>","DOI":"10.1902\/jop.2006.77.1.7","type":"journal-article","created":{"date-parts":[[2006,1,5]],"date-time":"2006-01-05T08:36:06Z","timestamp":1136450166000},"page":"7-14","source":"Crossref","is-referenced-by-count":79,"title":["Enamel Matrix Derivative and Coronal Flaps to Cover Marginal Tissue Recessions"],"prefix":"10.1002","volume":"77","author":[{"given":"Adriana","family":"Castellanos T.","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"de la Rosa R.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"de la Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul G.","family":"Caffesse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,1]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Oral Health of United States Adults","author":"Miller AJ","year":"1987"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.98"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.10.623"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1987.0236"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.6.489"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1978.49.7.351"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.9.864"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1996.1.1.671"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1973.44.4.248"},{"issue":"3","key":"e_1_2_8_11_1","first-page":"8","article-title":"Complete coverage of the denuded root surface with a one\u2010stage gingival graft","volume":"3","author":"Holbrook T","year":"1983","journal-title":"Int J Periodontics Restorative Dent"},{"issue":"2","key":"e_1_2_8_12_1","first-page":"14","article-title":"Root coverage using free soft tissue autograft following citric acid application. 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