{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:14:07Z","timestamp":1792149247050,"version":"4.4.0"},"reference-count":49,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Chemo\u2010mechanical treatment concepts have been developed to improve the outcome of non\u2010surgical periodontal therapy. Recently, the clinical additive value of a supersaturated chlorhexidine varnish was shown when used as an adjunct to staged scaling and root planing. The aim of this study was to investigate the clinical effects of a treatment strategy for chronic periodontitis based on a combination of same\u2010day full\u2010mouth root planing and subgingival chlorhexidine varnish administration.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A randomized, controlled, single\u2010blind, parallel trial was conducted on 33 non\u2010smoking chronic periodontitis patients. The control group received oral hygiene instructions and same\u2010day full\u2010mouth root planing. The test group received the same instructions and treatment; however, all pockets were disinfected using a chlorhexidine varnish. Clinical response parameters were recorded at baseline and after 1, 3, and 6 months.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Both groups showed significant reductions in probing depth following therapy (<jats:italic>P<\/jats:italic> &lt;0.001). There was no significant difference in full\u2010mouth probing depth between the groups at any examination point. However, when a site\u2010specific comparison was made, additive effects were found in the test group; an extra pocket reduction of 0.93 mm (<jats:italic>P<\/jats:italic> = 0.044) for initially deep pockets (\u22657 mm) was found at study termination. Additive clinical attachment gains seemed to be temporary. Impermanent extra pocket reductions and clinical attachment gains were found for initially medium\u2010deep pockets (4 to 6 mm).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The outcome of same\u2010day full\u2010mouth root planing may benefit from the subgingival administration of a highly concentrated chlorhexidine varnish, at least in terms of pocket reduction in initially deep sites (\u22657 mm).<\/jats:p>","DOI":"10.1902\/jop.2007.060221","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T14:08:16Z","timestamp":1172844496000},"page":"430-437","source":"Crossref","is-referenced-by-count":25,"title":["Subgingival Chlorhexidine Varnish Administration as an Adjunct to Same\u2010Day Full\u2010Mouth Root Planing. I. 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