{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T23:27:39Z","timestamp":1783380459667,"version":"3.54.6"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Placement of dental implants in the posterior maxilla has been associated with higher rates of failure that are due, in part, to the poor bone quality of this region. The purpose of the present study was the histologic and histomorphometric evaluation of the bone around a new implant surface treatment created by a deposition of nanometer\u2010sized calcium phosphate particles added to the dual acid\u2010etched surface.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> One custom\u2010made 2 \u00d7 10\u2010mm site evaluation implant (SEI) with this novel treatment surface (test) and one SEI with the dual acid\u2010etched surface without treatment (control) were placed in the posterior maxilla of 15 patients. All SEIs were retrieved after 2 months and evaluated under confocal laser scanning microscopy (CLSM) and by light microscopy for histomorphometric analysis of the bone\u2013implant contact (BIC).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Histologic observations in control SEIs showed formation of new bone around the implant surface; however, it was not always in direct contact with the entire perimeter of the threads. The mean BIC was 19% \u00b1 14.2%. Test SEIs showed peri\u2010implant bone tightly contacting the implant surface and better adapted to the threads. Three\u2010dimensional reconstruction of sections obtained using CLSM showed the intimacy of the contact between bone and test SEI surface through the entire thickness of the specimens. The mean BIC was 32.2% \u00b1 18.5%.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> After 2 months of healing, comparison of the BIC values showed a statistically significant greater mean BIC for test SEIs than for controls. The clinical implications of these results included shortening of the implant healing period and earlier loading protocols.<\/jats:p>","DOI":"10.1902\/jop.2007.060297","type":"journal-article","created":{"date-parts":[[2007,2,3]],"date-time":"2007-02-03T01:47:00Z","timestamp":1170467220000},"page":"209-218","source":"Crossref","is-referenced-by-count":110,"title":["Randomized, Controlled Histologic and Histomorphometric Evaluation of Implants With Nanometer\u2010Scale Calcium Phosphate Added to the Dual Acid\u2010Etched Surface in the Human Posterior 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