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Pseudomembranes may develop on the gingivae, and there may be periodontal involvement.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18\u2010year\u2010old girl.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> This approach had no benefit.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The question remains about how best to manage patients with hypoplasminogenemia.<\/jats:p>","DOI":"10.1902\/jop.2007.060422","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T08:27:43Z","timestamp":1180600063000},"page":"1164-1175","source":"Crossref","is-referenced-by-count":27,"title":["Hypoplasminogenemia With Ligneous Periodontitis: A Failed Local Therapeutic Approach"],"prefix":"10.1002","volume":"78","author":[{"given":"Idil","family":"Kurtulus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aslan","family":"Gokbuget","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Efeoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar","family":"Cintan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Tefs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Schuster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crispian","family":"Scully","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,6]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"96","volume-title":"25. 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