{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:58:17Z","timestamp":1773280697230,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The purpose of this randomized clinical trial was to evaluate the outcome of gingival recession therapy using the semilunar coronally repositioned flap (SCRF) with or without EDTA application for root surface biomodification.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Fifteen patients with bilateral Miller Class I buccal gingival recessions (\u22644.0 mm) were selected. Thirty teeth with recessions were assigned randomly to receive the semilunar coronally repositioned flap with (SCRF\u2010E group) or without (SCRF group) the application of an EDTA gel. Recession height (RH), recession width (RW), width (WKT) and thickness of keratinized tissue, probing depth, and clinical attachment level (CAL) were measured at baseline and 6 months post\u2010surgery. Patient perception of root sensitivity and postoperative pain also was evaluated.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Both treatments yielded significant improvements in terms of RH and RW decrease and CAL gain compared to baseline values. For SCRF\u2010E and SCRF, the average root coverage was 70.2% and 90.1%, respectively (<jats:italic>P<\/jats:italic> = 0.01), and the complete root coverage was 40.0% and 66.7%, respectively. Only the SCRF group had a significant (<jats:italic>P<\/jats:italic> &lt;0.05) increase in WKT. The SCRF group showed a greater reduction (<jats:italic>P<\/jats:italic> &lt;0.05) in RW and RH compared to the SCRF\u2010E group. No patient in either group reported any pain during the postoperative course; however, 6 months later, patients in the SCRF\u2010E group complained more of residual or new root sensitivity compared to patients in the SCRF group.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The use of EDTA gel as a root surface biomodifier agent negatively affected the outcome of root coverage with the SCRF.<\/jats:p>","DOI":"10.1902\/jop.2007.060507","type":"journal-article","created":{"date-parts":[[2007,8,31]],"date-time":"2007-08-31T07:46:35Z","timestamp":1188546395000},"page":"1695-1701","source":"Crossref","is-referenced-by-count":31,"title":["Root Surface Biomodification With EDTA for the Treatment of Gingival Recession With a Semilunar Coronally Repositioned Flap"],"prefix":"10.1002","volume":"78","author":[{"given":"Sandro","family":"Bittencourt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9rica Del Peloso","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enilson Ant\u00f4nio","family":"Sallum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Wilson","family":"Sallum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Francisco Humberto","family":"Nociti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Zaffalon","family":"Casati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,9]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"44","volume-title":"Glossary of Periodontal Terms","year":"2001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.6.489"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0757.2001.027001097.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.5.477"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01456.x"},{"key":"e_1_2_8_7_1","first-page":"169","article-title":"Treatment of gingival recessions by semilunar coronally positioned flap","volume":"55","author":"Casati MZ","year":"2001","journal-title":"Rev Assoc Paul Cir Dent"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1061-3315(18)30049-0"},{"key":"e_1_2_8_9_1","first-page":"68","article-title":"Desensitization of exposed root surfaces using a semilunar coronally positioned flap","volume":"48","author":"Thompson BK","year":"2000","journal-title":"Gen Dent"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050114"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.11.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.5.259"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.11.662"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.5.313"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.3.262"},{"key":"e_1_2_8_16_1","first-page":"353","article-title":"The effect of EDTA in attachment gain and root coverage","volume":"27","author":"Kassab MM","year":"2006","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1984.55.8.443"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345860650070301"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.10.1520"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00178.x"},{"key":"e_1_2_8_21_1","first-page":"607","article-title":"Surgical treatment of gingival recessions using Emdogain gel: Clinical procedure and case reports","volume":"23","author":"Abbas F","year":"2003","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.9.841"},{"key":"e_1_2_8_23_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_8_24_1","first-page":"107","article-title":"Gingival sulcus bleeding \u2013 A leading symptom in initial gingivitis","volume":"15","author":"M\u00fchlemann HR","year":"1971","journal-title":"Helv Odontol Acta"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1981.tb00956.x"},{"issue":"2","key":"e_1_2_8_26_1","first-page":"14","article-title":"Root coverage using the free soft tissue autograft following citric acid application. 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