{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:44:36Z","timestamp":1788871476911,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K24 DE\u201000419"],"award-info":[{"award-number":["K24 DE\u201000419"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    The purpose of the present longitudinal study was to evaluate the association between root proximity and the risk for alveolar bone loss (ABL).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    We used data from the Veterans Affairs Dental Longitudinal Study, a closed\u2010panel longitudinal cohort study of 1,231 men enrolled in 1968 with triennial follow\u2010up examinations. Periapical radiographs of mandibular incisors from subjects with \u226510 years of follow\u2010up were selected. Interradicular distance (IRD) at the cemento\u2010enamel junction and alveolar bone levels at baseline and last follow\u2010up were measured using digitized radiographs. The rate of progressive ABL was determined and expressed as millimeters per 10 years. Site\u2010specific multivariate regression models were fit to evaluate the association between IRD and ABL rate, adjusting for age and smoking. Empirical standard errors and generalized estimating equations were used to account for the correlation among sites within subjects.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    There were 473 dentate subjects, aged 28 to 71 years at baseline, with \u226510 years of follow\u2010up data available for analyses. The mean follow\u2010up time was 23 years. The mean IRD was 1.0 \u00b1 0.3 mm, and the mean ABL rate during 10 years was 0.61 \u00b1 0.59 mm. There was a significant non\u2010linear association between IRD and ABL rate (\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.005). Compared to sites with IRD \u22650.8 mm, sites with IRD &lt;0.6 mm were 28% (95% confidence interval [CI]: 11% to 48%) more likely to lose \u22650.5 mm of bone during 10 years (relative risk: 1.28 [95% CI: 1.11 to 1.48]) and 56% (95% CI: 11% to 117%) more likely to lose \u22651.0 mm of bone during 10 years (relative risk: 1.56 [95% CI: 1.11 to 2.17]).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    IRD &lt;0.8 mm is a significant local risk factor for alveolar bone loss in mandibular anterior teeth. Measurement of IRD may have important prognostic value in making treatment decisions.\n                  <\/jats:p>","DOI":"10.1902\/jop.2008.070477","type":"journal-article","created":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T08:57:21Z","timestamp":1207040241000},"page":"654-659","source":"Crossref","is-referenced-by-count":29,"title":["Root Proximity as a Risk Factor for Progression of Alveolar Bone Loss: The Veterans Affairs Dental Longitudinal Study"],"prefix":"10.1002","volume":"79","author":[{"given":"Taera","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanari","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha E.","family":"Nunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul I.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1979.50.12.665"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345860650061901"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1969.40.7.401"},{"key":"e_1_2_7_5_1","first-page":"8","article-title":"A consideration of root proximity","volume":"7","author":"Kramer GM","year":"1987","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.7.658"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1977.48.9.517"},{"key":"e_1_2_7_8_1","first-page":"8","article-title":"Interproximal periodontal disease \u2013 The embrasure as an etiologic factor","volume":"2","author":"Nevins M","year":"1982","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_9_1","first-page":"249","article-title":"Interproximal tooth morphology and its effect on plaque removal","volume":"20","author":"Smukler H","year":"1989","journal-title":"Quintessence Int"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1967.38.1.45"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0889-5406(87)90469-0"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1988.59.2.73"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00668.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00667.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/6.4.179"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2190\/WLL4-ET76-UQWN-R5FL"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1982.tb01133.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1983.tb00397.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345990780030401"},{"key":"e_1_2_7_20_1","first-page":"935","article-title":"American Academy of Periodontology. Epidemiology of periodontal diseases (position paper)","volume":"67","year":"1996","journal-title":"J Periodontol"},{"key":"e_1_2_7_21_1","article-title":"Mandibular anterior crowding and periodontal status","volume":"84","author":"Albloushi KA","year":"2005","journal-title":"J Dent Res"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2008.070477","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:39:35Z","timestamp":1760870375000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2008.070477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1902\/jop.2008.070477"],"URL":"https:\/\/doi.org\/10.1902\/jop.2008.070477","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}