{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:30:27Z","timestamp":1760920227218,"version":"build-2065373602"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004913","name":"Universit\u00e0 degli Studi di Palermo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009950","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The side effects of chlorhexidine (CHX) have stimulated the search for alternative antiplaque agents such as amine fluoride\/stannous fluoride (ASF) and essential oils (EO). The aim of the study was to investigate the plaque\u2010inhibiting effects of two commercially available mouthrinses containing ASF and EO, respectively.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> The study was an observer\u2010masked, randomized, 5 \u00d7 5 Latin square cross\u2010over design, balanced for carryover effects, involving 15 volunteers in a 4\u2010day plaque regrowth model. A 0.12% CHX rinse and a saline solution served as positive and negative controls, respectively. On day 1, subjects received professional prophylaxis, suspended oral hygiene measures, and commenced rinsing with their allocated rinses. On day 5, subjects were scored for disclosed plaque. The ASF rinse was tested at two dosages: 10 and 20 ml (ASF\u201010 and ASF\u201020, respectively).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The ASF and EO rinses showed a significant inhibition of plaque regrowth compared to saline (<jats:italic>P<\/jats:italic> &lt;0.0001), but the lowest plaque indices were obtained with the CHX product (<jats:italic>P<\/jats:italic> &lt;0.01). There were no significant differences among products containing ASF\u201010, ASF\u201020, and EO (<jats:italic>P<\/jats:italic> &gt;0.05). There was no correlation between the occurrence of side effects and the use of a particular rinse product (<jats:italic>P<\/jats:italic> &gt;0.2).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> ASF and EO mouthrinses exerted effective and similar plaque inhibition. The two dosages tested for ASF did not differ in plaque reduction. These findings, together with those from long\u2010term trials, suggest that ASF and EO rinses may represent effective alternatives to CHX rinse as adjuncts to oral hygiene.<\/jats:p>","DOI":"10.1902\/jop.2008.070583","type":"journal-article","created":{"date-parts":[[2008,7,2]],"date-time":"2008-07-02T08:54:28Z","timestamp":1214988868000},"page":"1177-1183","source":"Crossref","is-referenced-by-count":36,"title":["The Effects of an Essential Oil and an Amine Fluoride\/Stannous Fluoride Mouthrinse on Supragingival Plaque Regrowth"],"prefix":"10.1002","volume":"79","author":[{"given":"Giuseppe","family":"Pizzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"La Cara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Ester","family":"Licata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignazio","family":"Pizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"D'Angelo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00109.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0757.2002.280105.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00105.x"},{"key":"e_1_2_7_5_1","first-page":"464","volume-title":"The use of antiseptics in periodontal therapy","author":"Addy M","year":"2003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.30.s5.5.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00110.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1990.tb01108.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2004.0217"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb00640.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2001.0245"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00578.x"},{"key":"e_1_2_7_13_1","first-page":"351","article-title":"Comparative effectiveness of an essential oil mouthrinse and dental floss in controlling interproximal gingivitis and plaque","volume":"15","author":"Sharma NC","year":"2002","journal-title":"Am J Dent"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00371.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720080601"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007840100114"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01025.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00552.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00241.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290503.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb01797.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028002168.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.6.852"},{"key":"e_1_2_7_24_1","first-page":"331","article-title":"Influence of ethanol on the antibacterial and anti\u2010plaque efficacy of an amine\u2010fluoride\/stannous fluoride mouthrinse solution (in English and French)","volume":"20","author":"Arweiler NB","year":"2001","journal-title":"J Parodontol Implantol Orale"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.1999.260306.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1990.tb01092.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.10.1601"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1983.tb01270.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00103.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780110419"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1995.tb01282.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1970.41.1.41"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1962.0184"},{"key":"e_1_2_7_34_1","unstructured":"The World Medical Association. 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