{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:38:36Z","timestamp":1791909516854,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Guided bone regeneration (GBR) is a widely used procedure for augmenting alveolar ridge width prior to placement of endosseous implants. Various graft materials and barrier membranes (non\u2010resorbable and bioabsorbable) have been used in GBR. The aim of this study was to assess the performance of a new bioabsorbable, synthetic polyglycolic acid\/trimethylene carbonate (PGA\/TMC) barrier membrane with an increased absorption time in conjunction with a combination of assayed demineralized bone matrix and cortical cancellous chips uniformly dispersed in a thermoplastic biologic carrier.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> At 72 potential implant sites in 38 subjects, ridge width at the crest and 4 mm apical to the crest was measured before and 6 months after a GBR procedure using the long\u2010term (LT) PGA\/TMC membrane and an allograft in a thermoplastic carrier. Before placement of endosseous implants, 48 biopsy specimens were obtained from the augmentation sites and analyzed histomorphometrically.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The GBR procedure increased the mean ridge width at the crest from 2.4 to 5.2 mm. This 216% change from baseline was significant (<jats:italic>P<\/jats:italic> &lt;0.001). The mean width 4 mm apical to the crest increased from 4.4 to 7.5 mm, a significant (<jats:italic>P<\/jats:italic> &lt;0.001) 174% change. The histomorphometric analysis showed that the biopsy specimens consisted, on average, of 57% bone (36% graft material and 21% new bone) and 43% soft tissue and space.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Our findings suggest that the LT PGA\/TMC barrier membrane, used in conjunction with an allograft, provides lateral alveolar ridge augmentation comparable to that achieved with other materials without the necessity for bone\u2010graft harvesting or a second procedure to remove the barrier membrane.<\/jats:p>","DOI":"10.1902\/jop.2008.070595","type":"journal-article","created":{"date-parts":[[2008,7,2]],"date-time":"2008-07-02T08:54:28Z","timestamp":1214988868000},"page":"1133-1140","source":"Crossref","is-referenced-by-count":64,"title":["Clinical and Histologic Assessment of Lateral Alveolar Ridge Augmentation Using a Synthetic Long\u2010Term Bioabsorbable Membrane and an Allograft"],"prefix":"10.1002","volume":"79","author":[{"given":"Nicolaas C.","family":"Geurs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Korostoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Vassilopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae\u2010Heon","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"Jeffcoat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kellar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060238"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1563\/1548-1336(2001)027<0187:ESRFAR>2.3.CO;2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.9.1044"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00132.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2003.8.1.321"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(96)90113-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1999.tb00153.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2001.28.1.7"},{"key":"e_1_2_7_10_1","first-page":"358","article-title":"Report of 302 consecutive ridge augmentation procedures: Technical considerations and clinical results","volume":"13","author":"Fugazzotto PA","year":"1998","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1996.070212.x"},{"key":"e_1_2_7_12_1","first-page":"109","article-title":"Long\u2010term stability of osseointegrated implants in augmented bone: A 5\u2010year prospective study in partially edentulous patients","volume":"22","author":"Buser D","year":"2002","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_13_1","first-page":"34","article-title":"Implants in regenerated bone: Long\u2010term survival","volume":"18","author":"Nevins M","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(05)80623-X"},{"key":"e_1_2_7_15_1","first-page":"139","article-title":"Evaluation of a bioabsorbable physical barrier for guided bone regeneration. Part II. Material and a bone replacement graft","volume":"18","author":"Mellonig JT","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.2.257"},{"key":"e_1_2_7_17_1","first-page":"35","article-title":"Guided bone regeneration for implant placement using absorbable collagen membranes: Case presentations","volume":"6","author":"Cosci F","year":"1994","journal-title":"Pract Periodontics Aesthet Dent"},{"key":"e_1_2_7_18_1","first-page":"288","article-title":"Alveolar ridge augmentation with Bio\u2010Oss: A histologic study in humans","volume":"21","author":"Zitzmann NU","year":"2001","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.2.215"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-200009010-00011"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.11.1774"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1999.100409.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.id.0000204762.39826.0f"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01234.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.01029.x"},{"key":"e_1_2_7_26_1","first-page":"129","article-title":"Evaluation of a bioabsorbable physical barrier for guided bone regeneration. Part I. Material alone","volume":"18","author":"Mellonig JT","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.4.512"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2008.070595","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:07:25Z","timestamp":1760872045000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2008.070595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["10.1902\/jop.2008.070595"],"URL":"https:\/\/doi.org\/10.1902\/jop.2008.070595","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}