{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:03:36Z","timestamp":1779894216911,"version":"3.53.1"},"reference-count":50,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The concept of early implant placement is a treatment option in postextraction sites of single teeth in the anterior maxilla. Implant placement is performed after a soft tissue healing period of 4 to 8 weeks. Implant placement in a correct three\u2010dimensional position is combined with a simultaneous guided bone regeneration procedure to rebuild esthetic facial hard and soft tissue contours.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> In this retrospective, cross\u2010sectional study, 45 patients with an implant\u2010borne single crown in function for 2 to 4 years were recalled for examination. Clinical and radiologic parameters, routinely used in implant studies, were assessed.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> All 45 implants were clinically successful according to strict success criteria. The implants demonstrated ankylotic stability without signs of a peri\u2010implant infection. The peri\u2010implant soft tissues were clinically healthy as indicated by low mean plaque (0.42) and sulcus bleeding index (0.51) values. None of the implants revealed a mucosal recession on the facial aspect as confirmed by a clearly submucosal position of all implant shoulders. The mean distance from the mucosal margin to the implant shoulder was \u22121.93 mm on the facial aspect. The periapical radiographs showed stable peri\u2010implant bone levels, with a mean distance between the implant shoulder and the first bone\u2013implant contact of 2.18 mm.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> This retrospective study demonstrated successful treatment outcomes for all 45 implants examined. The mid\u2010term follow\u2010up of 2 to 4 years also showed that the risk for mucosal recession was low with this treatment concept. Prospective clinical studies are required to confirm these encouraging results.<\/jats:p>","DOI":"10.1902\/jop.2008.080071","type":"journal-article","created":{"date-parts":[[2008,9,4]],"date-time":"2008-09-04T20:03:05Z","timestamp":1220558585000},"page":"1773-1781","source":"Crossref","is-referenced-by-count":114,"title":["Early Implant Placement With Simultaneous Guided Bone Regeneration Following Single\u2010Tooth Extraction in the Esthetic Zone: A Cross\u2010Sectional, Retrospective Study in 45 Subjects With a 2\u2010 to 4\u2010Year Follow\u2010Up"],"prefix":"10.1002","volume":"79","author":[{"given":"Daniel","family":"Buser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Bornstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Peter","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Gr\u00fctter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs C.","family":"Belser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1990.010105.x"},{"key":"e_1_2_7_3_1","first-page":"627","article-title":"Osseointegrated implants in the treatment of partially edentulous jaws: A prospective 5\u2010year multicenter study","volume":"9","author":"Lekholm U","year":"1994","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1997.080302.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2000.110207.x"},{"key":"e_1_2_7_6_1","first-page":"633","article-title":"The longitudinal clinical effectiveness of ITI solid\u2010screw implants in partially edentulous patients: A 5\u2010year follow\u2010up report","volume":"15","author":"Behneke A","year":"2000","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01209.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00131.x"},{"key":"e_1_2_7_9_1","first-page":"43","article-title":"Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations","volume":"19","author":"Buser D","year":"2004","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_10_1","unstructured":"Mayfield LJA. 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