{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:40:56Z","timestamp":1790023256895,"version":"4.0.1"},"reference-count":55,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009068","name":"Universit\u00e4t Bern","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009068","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The bacterial colonization of the oral mucosa was evaluated in patients with asymptomatic oral lichen planus (OLP) and compared to the microbiologic status in mucosally healthy subjects.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Bacteria from patients with clinically and histopathologically diagnosed OLP from the Stomatology Service, Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, were collected with a non\u2010invasive swab system. Samples were taken from OLP lesions on the gingiva and from non\u2010affected sites on the contralateral side of the mouth. The control population did not have OLP and was recruited from the student clinic. All samples were processed with the checkerboard DNA\u2010DNA hybridization method using well\u2010defined bacterial species for the analysis.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Significantly higher bacterial counts of <jats:italic>Bacteroides ureolyticus<\/jats:italic> (<jats:italic>P<\/jats:italic> = 0.001), <jats:italic>Dialister<\/jats:italic> species (sp.) (<jats:italic>P<\/jats:italic> = 0.006), <jats:italic>Staphylococcus haemolyticus<\/jats:italic> (<jats:italic>P<\/jats:italic> = 0.007), and <jats:italic>Streptococcus agalactiae<\/jats:italic> (<jats:italic>P<\/jats:italic> = 0.006) were found in samples taken from OLP lesions compared to sites with no clinical evidence of OLP. Significantly higher bacterial counts were found for <jats:italic>Capnocytophaga sputigena<\/jats:italic>, <jats:italic>Eikenella corrodens<\/jats:italic>, <jats:italic>Lactobacillus crispatus<\/jats:italic>, <jats:italic>Mobiluncus curtisii<\/jats:italic>, <jats:italic>Neisseria mucosa<\/jats:italic>, <jats:italic>Prevotella bivia<\/jats:italic>, <jats:italic>Prevotella intermedia<\/jats:italic>, and <jats:italic>S. agalactiae<\/jats:italic> at sites with lesions in subjects with OLP compared to sites in control subjects (<jats:italic>P<\/jats:italic> &lt;0.001).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Microbiologic differences were found between sites with OLP and sites in subjects without a diagnosis of OLP. Specifically, higher counts of staphylococci and <jats:italic>S. agalactiae<\/jats:italic> were found in OLP lesions.<\/jats:p>","DOI":"10.1902\/jop.2008.080303","type":"journal-article","created":{"date-parts":[[2008,12,4]],"date-time":"2008-12-04T07:12:25Z","timestamp":1228374745000},"page":"2347-2355","source":"Crossref","is-referenced-by-count":37,"title":["Microbiological Findings in Subjects With Asymptomatic Oral Lichen Planus: A Cross\u2010Sectional Comparative Study"],"prefix":"10.1002","volume":"79","author":[{"given":"Michael M.","family":"Bornstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basir","family":"Hakimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. 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