{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:22:02Z","timestamp":1791091322259,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Early implant placement is one of the treatment options in postextraction sites in the anterior maxilla. Implant placement is performed after a soft tissue healing period of 4 to 8 weeks. Implant placement is combined with a simultaneous guided bone regeneration (GBR) procedure to rebuild esthetic facial hard and soft tissue contours.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> In this prospective case\u2010series study, 20 consecutive patients treated with an implant\u2010borne single crown were prospectively followed for 12 months. Clinical, radiologic, and esthetic parameters were recorded to assess treatment outcomes.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> At the 12\u2010month examination, all 20 implants were successfully integrated, demonstrating ankylotic stability and healthy peri\u2010implant soft tissues as documented by standard parameters. The esthetic outcomes assessed by a pink esthetic score (PES) and a white esthetic score (WES) demonstrated pleasing results overall. The WES values were slightly superior to the PES values. The periapical radiographs showed minimal crestal bone loss around the used bone level implants, with mean bone loss of 0.18 mm at 12 months. Only one implant showed &gt;0.5 mm bone loss, combined with minor mucosal recession of 0.5 to 1.0 mm.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> This prospective case series study evaluating the concept of early implant placement demonstrated successful tissue integration for all 20 implants. The short\u2010term follow\u2010up of 12 months revealed pleasing esthetic outcomes overall, as assessed by objective parameters. The risk for mucosal recession was low; only one patient showed minor recession of the facial mucosa. These encouraging results need to be confirmed with 3\u2010 and 5\u2010year follow\u2010up examinations.<\/jats:p>","DOI":"10.1902\/jop.2009.080360","type":"journal-article","created":{"date-parts":[[2008,12,30]],"date-time":"2008-12-30T06:33:32Z","timestamp":1230618812000},"page":"152-162","source":"Crossref","is-referenced-by-count":178,"title":["Early Implant Placement With Simultaneous Guided Bone Regeneration Following Single\u2010Tooth Extraction in the Esthetic Zone: 12\u2010Month Results of a Prospective Study With 20 Consecutive Patients"],"prefix":"10.1002","volume":"80","author":[{"given":"Daniel","family":"Buser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Halbritter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Hart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Bornstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Gr\u00fctter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivianne","family":"Chappuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs C.","family":"Belser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00131.x"},{"key":"e_1_2_7_3_1","first-page":"199","article-title":"Predictable single tooth peri\u2010implant esthetics: Five diagnostic keys","volume":"22","author":"Kois JC","year":"2001","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_7_4_1","first-page":"43","article-title":"Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations","volume":"19","author":"Buser D","year":"2004","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_5_1","first-page":"11","volume-title":"Diagnostic factors for esthetic risk assessment","author":"Martin WC","year":"2006"},{"key":"e_1_2_7_6_1","first-page":"520","volume-title":"Immediate, delayed and late submerged and transmucosal implants","author":"Mayfield LJA","year":"1999"},{"key":"e_1_2_7_7_1","first-page":"12","article-title":"Immediate or early placement of implants following tooth extraction: Review of biologic basis, clinical procedures, and outcomes","volume":"19","author":"Chen ST","year":"2004","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_8_1","first-page":"440","article-title":"Early implant placement following single\u2010tooth extraction in the esthetic zone: Biologic rationale and surgical procedures","volume":"28","author":"Buser D","year":"2008","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.08.022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01388.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.04.006"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01413.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.080071"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.2000.011S1059.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1987.tb00298.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1990.010105.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01209.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1992.030405.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080435"},{"key":"e_1_2_7_20_1","first-page":"65","article-title":"A simple sequentially multiple test procedure","volume":"6","author":"Holm S","year":"1979","journal-title":"Scand J Stat"},{"key":"e_1_2_7_21_1","unstructured":"The R project for statistical computing. 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