{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T13:40:39Z","timestamp":1773150039069,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> There are common risk factors for periodontal disease and cardiovascular disease in elderly patients. Some studies reported that a low total cholesterol (TC) serum level is associated with a higher level of death in the elderly. The purpose of this study was to investigate the relationship between serum lipids and periodontal disease in non\u2010smoking elderly patients.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Two hundred thirty\u2010four non\u2010smokers (63 males and 171 females) participated in this study. Multiple regression analysis was performed to evaluate the relationship between serum lipids and periodontitis and between serum lipids and inflammatory factors. The percentage of sites with probing depth (PD) \u22654 mm, clinical attachment level (CAL) \u22654 mm, and bleeding on probing (BOP) were used as dependent variables. TC, high\u2010density lipoprotein cholesterol (HDL\u2010C), gender, and the number of teeth present were included in the model as independent variables in the first analysis. TC, HDL\u2010C, and low\u2010density lipoprotein cholesterol (LDL\u2010C) were used as dependent variables. Albumin, inorganic phosphorus, calcium, and C\u2010reactive protein were used as independent variables in the second analysis.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> According to the results of the multiple linear regression analysis, TC was associated with the percentage of sites with PD \u22654 mm (<jats:italic>P<\/jats:italic> &lt;0.01; \u03b2 = \u22120.19), CAL \u22654 mm (<jats:italic>P<\/jats:italic> &lt;0.01; \u03b2 = \u22120.20), and BOP (<jats:italic>P<\/jats:italic> = 0.03; \u03b2 = \u22120.16). HDL\u2010C and LDL\u2010C have a significant association with inflammatory markers and inorganic phosphorus and calcium, respectively.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Higher TC is associated with a lower prevalence of periodontitis in non\u2010smoking elderly patients.<\/jats:p>","DOI":"10.1902\/jop.2009.080584","type":"journal-article","created":{"date-parts":[[2009,4,30]],"date-time":"2009-04-30T12:45:43Z","timestamp":1241095543000},"page":"740-748","source":"Crossref","is-referenced-by-count":11,"title":["The Relationship Between Serum Lipids and Periodontitis in Elderly Non\u2010Smokers"],"prefix":"10.1002","volume":"80","author":[{"given":"Aki","family":"Izumi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Yoshihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshinobu","family":"Hirotomi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410090025004"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.08.022"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(93)90263-T"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6879.688"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.10s.1123"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530070037026"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808133390717"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.1999.261006.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028009865.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53106.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2001.49229.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2389.2003.51313.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00354-1"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1987.03390160062027"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113157"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90034-K"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00881.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04430-9"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00791.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20001001)88:1<1::AID-IJC1>3.0.CO;2-D"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-6047.2002.00256.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2003.10719293"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.5005\/jcdp-6-3-78"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242005000400009"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910508400312"},{"key":"e_1_2_7_27_1","first-page":"32","article-title":"Relationship between blood triglyceride levels and periodontal status","volume":"21","author":"Morita M","year":"2004","journal-title":"Community Dent Health"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1991.tb01649.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2005.05.008"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000232522.47018.a6"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000146094.59640.13"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.17.11.2910"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.72.9.1221"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/36.5.1014"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(83)90215-9"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01626539"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(90)90273-F"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(90)90108-O"},{"key":"e_1_2_7_39_1","first-page":"219","article-title":"Cortical bone mineral density in the mandible and osteoporosis status in postmenopausal women","volume":"101","author":"Klemetti E","year":"1993","journal-title":"Scand J Dent Res"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2009.080584","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:02:02Z","timestamp":1760871722000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2009.080584"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1902\/jop.2009.080584"],"URL":"https:\/\/doi.org\/10.1902\/jop.2009.080584","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}