{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:26:06Z","timestamp":1761708366670,"version":"build-2065373602"},"reference-count":47,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> A platelet concentrate graft (PCG) was applied underneath the barrier membrane in guided tissue regeneration (GTR)\u2013based root coverage procedures. The purpose of this case study was to assess the effectiveness of the technique and the long\u2010term outcomes.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Thirty\u2010seven Miller Class I or II recession defects in six patients were treated using the PCG and a collagen membrane covered by an advanced mucogingival flap. Clinical parameters, such as vertical gingival recession depth (VRD), clinical attachment level (CAL), probing depth (PD), and width of keratinized tissue (WKT), were recorded presurgery (at baseline [BL]) and at 6 and 36 months of follow\u2010up. The Wilcoxon signed\u2010rank test and the Mann\u2010Whitney test were used to assess statistical significance (\u03b1 = 0.05).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Between BL and 6 months, there was a statistically significant reduction in VRD (from 2.81 \u00b1 0.88 mm to 0.30 \u00b1 0.48 mm) and PD (from 2.59 \u00b1 0.50 mm to 1.14 \u00b1 0.35 mm), as well as an improvement in CAL (from 5.41 \u00b1 0.86 mm to 1.43 \u00b1 0.66 mm). These results remained stable over the following 30 months. There was no statistically significant change in WKT during the initial 6 months; however, the increase in WKT was statistically significant at the 36\u2010month follow\u2010up. When comparing the healing between the maxillary and mandibular teeth at 6 months, the VRD reduction was statistically significantly greater in the maxillary teeth, but the difference was not statistically significant 30 months later. The average root coverage at 6 and 36 months was 89.86% \u00b1 15.85% and 85.86% \u00b1 18.16%, respectively, with complete root coverage in 24 (64.86%) and 21 (56.76%) of the 37 teeth.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The GTR\u2013based technique using PCG was effective in reducing gingival recession. 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