{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T16:35:07Z","timestamp":1770827707481,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The identification of <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic> (previously <jats:italic>Actinobacillus actinomycetemcomitans<\/jats:italic>) serotypes may add some important information to the understanding of the pathogenetic background of severe periodontal infections. This study compared serotypes of <jats:italic>A. actinomycetemcomitans<\/jats:italic> in two groups of periodontal patients with different ethnic backgrounds.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A total of 194 patients (96 Germans and 98 Koreans) with aggressive or severe chronic periodontitis participated in the study. Microbiologic analysis of pooled samples from subgingival plaque was performed by using a real\u2010time polymerase chain reaction (PCR) test for <jats:italic>A. actinomycetemcomitans<\/jats:italic>. In patients who tested positive for <jats:italic>A. actinomycetemcomitans<\/jats:italic>, serotypes (a through f) were determined by nucleic acid\u2010based methods.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The prevalence of patients who tested positive for <jats:italic>A. actinomycetemcomitans<\/jats:italic> with the real\u2010time PCR was comparable in both groups (Germans: 27.0%; Koreans: 22.2%). In German patients, the serotypes detected most frequently were b (33.3%), c (25.0%), and a (20.8%), whereas in Korean patients, the serotype distribution was different, with serotypes c (61.9%) and d (19.0%) accounting for &gt;80% of the complete serotype spectrum.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Even if the percentage of patients who tested positive for <jats:italic>A. actinomycetemcomitans<\/jats:italic> was identical in patients with generalized aggressive and severe chronic periodontitis and different ethnic backgrounds, the distribution of <jats:italic>A. actinomycetemcomitans<\/jats:italic> serotypes may exhibit marked differences.<\/jats:p>","DOI":"10.1902\/jop.2009.090241","type":"journal-article","created":{"date-parts":[[2009,12,7]],"date-time":"2009-12-07T08:57:14Z","timestamp":1260176234000},"page":"2020-2027","source":"Crossref","is-referenced-by-count":31,"title":["Serotypes of <i>Aggregatibacter actinomycetemcomitans<\/i> in Patients With Different Ethnic Backgrounds"],"prefix":"10.1002","volume":"80","author":[{"given":"Ti\u2010Sun","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Eickholz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigrun","family":"Eick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong Kwan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1983.54.12.707"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb01348.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64207-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1991.tb00462.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1993.tb00556.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345940730080501"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-140-8-2049"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1992.tb00588.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.41.1.19-27.1983"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.33.2.395-401.1995"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/08959374880020021101"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.39"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02027.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.9.506"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1993.tb00657.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.62.2.501-508.1994"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.64.7.2724-2729.1996"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.9.998"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.6.912"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.12.3037-3042.1997"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345010800062001"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.1.38"},{"key":"e_1_2_8_25_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1991.tb02067.x"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.9.827"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.10.797"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.11.3504-3508.1999"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.9.5375-5384.2001"},{"key":"e_1_2_8_31_1","first-page":"365","volume-title":"Primer3 on the WWW for General Users and for Biologist Programmers","author":"Krawetz S","year":"2000"},{"key":"e_1_2_8_32_1","unstructured":"Primer3. Available at:http:\/\/frodo.wi.mit.edu\/primer3\/input.htm. Accessed November 13 2009."},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.34.6.1576-1578.1996"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.1999.260803.x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.2003.00034.x"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2002.201238.x"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2007.00354.x"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1998.tb00701.x"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028009886.x"},{"key":"e_1_2_8_40_1","first-page":"113","article-title":"Isolation frequency and serotype distribution of mutans streptococci and Actinobacillus actinomycetemcomitans, and clinical periodontal status in Finnish and Vietnamese children","volume":"102","author":"Holtta P","year":"1994","journal-title":"Scand J Dent Res"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.6.803"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1997.tb00578.x"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1997.tb00360.x"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1996.tb01415.x"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1988.tb00596.x"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02419.x"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2009.090241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:13:44Z","timestamp":1760879624000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2009.090241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":45,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.1902\/jop.2009.090241"],"URL":"https:\/\/doi.org\/10.1902\/jop.2009.090241","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}